Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA098731-02
Application #
6698566
Study Section
Experimental Therapeutics Subcommittee 1 (ET)
Program Officer
Hecht, Toby T
Project Start
2003-01-21
Project End
2004-04-30
Budget Start
2004-01-01
Budget End
2004-04-30
Support Year
2
Fiscal Year
2004
Total Cost
$289,361
Indirect Cost
Name
Mayo Clinic, Rochester
Department
Type
DUNS #
006471700
City
Rochester
State
MN
Country
United States
Zip Code
55905
Luo, Liqun; Zhu, Gefeng; Xu, Haiying et al. (2015) B7-H3 Promotes Pathogenesis of Autoimmune Disease and Inflammation by Regulating the Activity of Different T Cell Subsets. PLoS One 10:e0130126
Zhu, Yuwen; Yao, Sheng; Iliopoulou, Bettina P et al. (2013) B7-H5 costimulates human T cells via CD28H. Nat Commun 4:2043
Flies, Dallas B; Wang, Shengdian; Xu, Haiying et al. (2011) Cutting edge: A monoclonal antibody specific for the programmed death-1 homolog prevents graft-versus-host disease in mouse models. J Immunol 187:1537-41
Zhu, Yuwen; Yao, Sheng; Chen, Lieping (2011) Cell surface signaling molecules in the control of immune responses: a tide model. Immunity 34:466-78
Yi, Kyung H; Chen, Lieping (2009) Fine tuning the immune response through B7-H3 and B7-H4. Immunol Rev 229:145-51
Azuma, Takeshi; Zhu, Gefeng; Xu, Haiying et al. (2009) Potential role of decoy B7-H4 in the pathogenesis of rheumatoid arthritis: a mouse model informed by clinical data. PLoS Med 6:e1000166
Zhu, Gefeng; Augustine, Mathew M; Azuma, Takeshi et al. (2009) B7-H4-deficient mice display augmented neutrophil-mediated innate immunity. Blood 113:1759-67
Kryczek, Ilona; Wei, Shuang; Zhu, Gefeng et al. (2007) Relationship between B7-H4, regulatory T cells, and patient outcome in human ovarian carcinoma. Cancer Res 67:8900-5
Jun, Her; Seo, Su K; Jeong, Hye-Young et al. (2005) B7-H1 (CD274) inhibits the development of herpetic stromal keratitis (HSK). FEBS Lett 579:6259-64
Luo, Liqun; Chapoval, Andrei I; Flies, Dallas B et al. (2004) B7-H3 enhances tumor immunity in vivo by costimulating rapid clonal expansion of antigen-specific CD8+ cytolytic T cells. J Immunol 173:5445-50

Showing the most recent 10 out of 12 publications