Colorectal cancer (CRC) is a highly preventable cancer, yet it is a leading cause of cancer death in the US. Disparities in CRC morbidity and mortality by socio-economic position and race/ethnicity have been documented. While individual health behaviors do not fully explain differentials in mortality by socioeconomic position, they are significant determinants of societal patterns of risk. These patterns reflect the social context, or larger structural forces that shape the texture of people's day-to-day realities, and that include an array of social and material resources that ultimately have profound effects on health. Little research has been conducted to date to examine how best to intervene within a social context, or to determine what settings are best for addressing contextual factors. Low-income housing sites have great potential as a channel for addressing disparities, as many social contextual factors occur in the housing setting. The goal of this project is to evaluate an intervention designed to address colorectal cancer prevention (CRC) through low income housing sites. A key aspect of the intervention is to determine ways in which addressing the social context in low income, ethnically diverse populations may address disparities in CRC prevention. This study is a randomized controlled trial that will be conducted in 10 diverse low income housing sites; eligible residents will be enrolled in a cohort and followed; housing site will be the unit of randomization and intervention. The intervention conditions are: (1) a social contextual, housing site-based intervention, that addresses individual, organizational, and systems-level factors that influence participation in CRC prevention activities; or (2) minimal treatment control. The primary outcomes are physical activity and participation in colorectal cancer screening. Of note, both interventions will offer equivalent access to CRC screening. A key goal of this project is to determine if adding on-site outreach and contextually focused activities yield greater overall changes in the study outcomes and is more cost-effective, compared to self-help materials plus efforts to reduce barriers to screening access.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA098864-04
Application #
7112243
Study Section
Special Emphasis Panel (ZRG1-RPHB-2 (01))
Program Officer
Chollette, Veronica
Project Start
2003-08-06
Project End
2008-05-31
Budget Start
2006-06-01
Budget End
2007-05-31
Support Year
4
Fiscal Year
2006
Total Cost
$710,704
Indirect Cost
Name
Dana-Farber Cancer Institute
Department
Type
DUNS #
076580745
City
Boston
State
MA
Country
United States
Zip Code
02215
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De Jesus, Maria; Puleo, Elaine; Shelton, Rachel C et al. (2010) Factors associated with colorectal cancer screening among a low-income, multiethnic, highly insured population: does provider's understanding of the patient's social context matter? J Urban Health 87:236-243
De Jesus, Maria; Puleo, Elaine; Shelton, Rachel C et al. (2010) Associations between perceived social environment and neighborhood safety: Health implications. Health Place 16:1007-13
Shelton, Rachel C; Puleo, Elaine; Bennett, Gary G et al. (2009) The association between racial and gender discrimination and body mass index among residents living in lower-income housing. Ethn Dis 19:251-7
Shelton, Rachel C; Puleo, Elaine; Bennett, Gary G et al. (2009) Racial discrimination and physical activity among low-income-housing residents. Am J Prev Med 37:541-5

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