Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA098925-02
Application #
6693022
Study Section
Immunobiology Study Section (IMB)
Program Officer
Mccarthy, Susan A
Project Start
2003-01-01
Project End
2007-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
2
Fiscal Year
2004
Total Cost
$360,450
Indirect Cost
Name
California Institute of Technology
Department
Type
Schools of Arts and Sciences
DUNS #
009584210
City
Pasadena
State
CA
Country
United States
Zip Code
91125
Rothenberg, Ellen V (2015) Immune Cell Identity: Perspective from a Palimpsest. Perspect Biol Med 58:205-28
Scripture-Adams, Deirdre D; Damle, Sagar S; Li, Long et al. (2014) GATA-3 dose-dependent checkpoints in early T cell commitment. J Immunol 193:3470-91
Rothenberg, Ellen V (2011) T cell lineage commitment: identity and renunciation. J Immunol 186:6649-55
Rothenberg, Ellen V; Scripture-Adams, Deirdre D (2008) Competition and collaboration: GATA-3, PU.1, and Notch signaling in early T-cell fate determination. Semin Immunol 20:236-46
Georgescu, Constantin; Longabaugh, William J R; Scripture-Adams, Deirdre D et al. (2008) A gene regulatory network armature for T lymphocyte specification. Proc Natl Acad Sci U S A 105:20100-5
Taghon, Tom; Rothenberg, Ellen V (2008) Molecular mechanisms that control mouse and human TCR-alphabeta and TCR-gammadelta T cell development. Semin Immunopathol 30:383-98
Rothenberg, Ellen V; Moore, Jonathan E; Yui, Mary A (2008) Launching the T-cell-lineage developmental programme. Nat Rev Immunol 8:9-21
Tydell, C Chace; David-Fung, Elizabeth-Sharon; Moore, Jonathan E et al. (2007) Molecular dissection of prethymic progenitor entry into the T lymphocyte developmental pathway. J Immunol 179:421-38
Taghon, Tom; Yui, Mary A; Rothenberg, Ellen V (2007) Mast cell lineage diversion of T lineage precursors by the essential T cell transcription factor GATA-3. Nat Immunol 8:845-55
Rothenberg, Ellen V (2007) Negotiation of the T lineage fate decision by transcription-factor interplay and microenvironmental signals. Immunity 26:690-702

Showing the most recent 10 out of 16 publications