Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA099951-05S1
Application #
6894861
Study Section
Special Emphasis Panel (ZRG1)
Program Officer
Rosenfeld, Bobby
Project Start
2004-03-01
Project End
2007-07-31
Budget Start
2004-03-01
Budget End
2004-07-31
Support Year
5
Fiscal Year
2004
Total Cost
$32,137
Indirect Cost
Name
University of Medicine & Dentistry of NJ
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
617022384
City
Piscataway
State
NJ
Country
United States
Zip Code
08854
Park, Hye-Jin; Zheng, Haiyan; Kulkarni, Diptee et al. (2008) Identification of phosphorylation sites of TOPORS and a role for serine 98 in the regulation of ubiquitin but not SUMO E3 ligase activity. Biochemistry 47:13887-96
Guan, Bin; Pungaliya, Pooja; Li, Xiang et al. (2008) Ubiquitination by TOPORS regulates the prostate tumor suppressor NKX3.1. J Biol Chem 283:4834-40
Pungaliya, Pooja; Kulkarni, Diptee; Park, Hye-Jin et al. (2007) TOPORS functions as a SUMO-1 E3 ligase for chromatin-modifying proteins. J Proteome Res 6:3918-23
Desai, Shyamal D; Haas, Arthur L; Wood, Laurence M et al. (2006) Elevated expression of ISG15 in tumor cells interferes with the ubiquitin/26S proteasome pathway. Cancer Res 66:921-8