Cancer patients frequently report high levels of distress and unmet psychosocial needs, both of which can contribute to negative health outcomes. Addressing this problem with psychosocial group interventions has had documented success in several cancer populations. The proposed study is designed to test the efficacy of a recently developed, innovative, multi-modal group program for cancer patients, and to compare it to a standard cancer support group. The intervention, mindfulness-based art therapy (MBAT), was developed with the specific purpose of enhancing both the supportive and expressive aspects of the typically available group treatment. This study is intended to build upon the very encouraging results of a recently completed clinical trial (N=111) that demonstrated highly significant improvements in symptoms of psychological distress and quality of life in a heterogeneous group of cancer patients who received the MBAT intervention, as compared to a similar group who received no intervention. In the proposed study, 339 women will be enrolled (226 with breast cancer and 113 with other cancer diagnoses). The breast cancer patients will be randomized to either the MBAT experimental arm or a standardized breast cancer support group. The women with other cancer diagnoses will be consecutively assigned to the MBAT group. Groups will be compared on measures of psychological distress (SCL-90-R) and key aspects of health-related quality of life (SF-36, general health and mental health subscales). In addition, for the MBAT group, comparisons on these measures will be made between breast and non-breast cancer patients . Secondarily, we will consider treatment effects on autonomic nervous system and immune system functioning, fatigue, and traumatic stress, and examine the role of social support and personality factors. This study is a crucial step towards testing efficacy and assessing for potential advantages of MBAT over a standard support group format. Our long-range goal is to find innovative means of improving the psychosocial health of cancer survivors.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA111832-03
Application #
7270628
Study Section
Special Emphasis Panel (ZRG1-RPHB-J (06))
Program Officer
Jeffery, Diana D
Project Start
2005-09-01
Project End
2010-05-31
Budget Start
2007-07-01
Budget End
2008-05-31
Support Year
3
Fiscal Year
2007
Total Cost
$443,377
Indirect Cost
Name
Thomas Jefferson University
Department
Psychiatry
Type
Schools of Medicine
DUNS #
053284659
City
Philadelphia
State
PA
Country
United States
Zip Code
19107
Prioli, Katherine M; Pizzi, Laura T; Kash, Kathryn M et al. (2017) Costs and Effectiveness of Mindfulness-Based Art Therapy versus Standard Breast Cancer Support Group for Women with Cancer. Am Health Drug Benefits 10:288-295
Monti, Daniel A; Kash, Kathryn M; Kunkel, Elisabeth J et al. (2013) Psychosocial benefits of a novel mindfulness intervention versus standard support in distressed women with breast cancer. Psychooncology 22:2565-75
Monti, Daniel A; Kash, Kathryn M; Kunkel, Elisabeth J S et al. (2012) Changes in cerebral blood flow and anxiety associated with an 8-week mindfulness programme in women with breast cancer. Stress Health 28:397-407