Following treatment, the vast majority of Pca survivors suffer from treatment-related symptomatology, specifically urinary and sexual dysfunction, in addition to facing psychosocial and practical challenges. There is a need for comprehensive programs with demonstrated efficacy to help patients cope with these challenges. We propose to develop and evaluate a comprehensive and innovative multimedia program designed to facilitate the post-treatment transition into survivorship. The design of the proposed intervention, the Virtual Survivorship Resource Center for Prostate Cancer (VSRC-PC), will be theoretically based on the team's Cognitive-Social Health Information Processing Model. The VSRC-PC will focus on promoting adaptive coping within four key post-treatment domains: 1) Physical Dysfunction (e.g., physical symptoms);2) Emotional Well- Being (e.g., fear of recurrence);3) Interpersonal Concerns (e.g., sexual intimacy issues);and 4) Practical Barriers (e.g., medical follow-up challenges). Content for these domains will be organized in a virtual resource center and will consist of: 1) provision of related information through text, graphics, voice-overs, and animation;2) videos of health care experts answering frequently asked questions;3) videos of prostate cancer survivors describing their experiences and modeling competencies and coping strategies;and 4) skills training to improve communication between Pca survivors and family and healthcare providers. Program content will be developed through literature and evidence-based content review, expert input, and input from multi-ethnic survivor focus groups. To ensure adequate and appropriate program content and optimal functionality, an iterative process of review, revision, and user and usability testing will be employed. Intervention efficacy will be evaluated through a two-arm, prospective randomized controlled trial. A total of 600 patients will complete the study. Data will be collected at baseline, and at 1-, 3- and 6- month follow-up. The primary outcome variable will be adaptive coping, and the secondary outcome will be maladaptive coping. A theory-based test of mediators of intervention effects (e.g., self-efficacy), and moderators (e.g., monitoring style) will also be performed. The proposed research will be the first RCT to evaluate not only a comprehensive but also highly disseminable and self-sustaining intervention for facilitating post-treatment adaptation among early-stage Pca survivors.

Public Health Relevance

Prostate cancer is the most common cancer among US men and treatment effects pose formidable quality of life and health care problems for men transitioning from active treatment to early follow-up. Yet, few interventions focus on this pivotal transition. We propose an innovative, self-paced web-based educational program to facilitate prostate cancer survivors'skill training and enhance their self-coping skills. The intervention has great potential to improve survivors'quality of life using a format that is easily accessible and readily portable for wide dissemination in the health care delivery system.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Research Project (R01)
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Behavioral Medicine, Interventions and Outcomes Study Section (BMIO)
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Hesse, Bradford
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Research Institute of Fox Chase Cancer Center
United States
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Diefenbach, Michael A; Benedict, Catherine; Miller, Suzanne M et al. (2018) Examining the impact of a multimedia intervention on treatment decision-making among newly diagnosed prostate cancer patients: results from a nationwide RCT. Transl Behav Med 8:876-886
Christian, Allison H; O'Malley, Denalee; Barac, Ana et al. (2017) Cardiovascular risk and communication among early stage breast cancer survivors. Patient Educ Couns 100:1360-1366
Roussi, Pagona; Miller, Suzanne M; Giri, Veda N et al. (2016) Effects of a randomized trial comparing standard and enhanced counseling for men at high risk of prostate cancer as a function of race and monitoring style. J Health Psychol :1359105316671188
Hui, Siu-Kuen Azor; Miller, Suzanne M; Hazuda, Leah et al. (2016) Novel Method for Recruiting Representative At-Risk Individuals into Cancer Prevention Trials: Online Health Risk Assessment in Employee Wellness Programs. J Cancer Educ 31:421-9
Christian, Allison; Hudson, Shawna V; Miller, Suzanne M et al. (2015) Perceptions of Primary Care Among Breast Cancer Survivors: The Effects of Weight Status. Health Serv Res Manag Epidemiol 2:
Miller, Suzanne M (2015) Monitoring processing style: to see or not to see. Eur J Pain 19:449-50
Sherman, Kerry A; Miller, Suzanne M; Roussi, Pagona et al. (2015) Factors predicting adherence to risk management behaviors of women at increased risk for developing lymphedema. Support Care Cancer 23:61-9
Leiter, Amanda; Diefenbach, Michael A; Doucette, John et al. (2015) Clinical trial awareness: Changes over time and sociodemographic disparities. Clin Trials 12:215-23
Miller, Suzanne M; Hudson, Shawna V; Hui, Siu-Kuen Azor et al. (2015) Development and preliminary testing of PROGRESS: a Web-based education program for prostate cancer survivors transitioning from active treatment. J Cancer Surviv 9:541-53
Hudson, Shawna V; O'Malley, Denalee M; Miller, Suzanne M (2015) Achieving optimal delivery of follow-up care for prostate cancer survivors: improving patient outcomes. Patient Relat Outcome Meas 6:75-90

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