One of the greatest difficulties experienced by survivors of head and neck cancer (HNC) relates to verbal communication. However, standard HNC outcome measures do not capture how individuals communicate in everyday life situations, or communicative participation. Recently, our research team began to address this critical gap through initial validation of a tool that measures communicative participation: the Communicative Participation Item Bank (CPIB). Yet, before becoming a gold standard measure for treatment efficacy research, an outcome measure must be able to detect changes in function over time. Clinicians must also know what the smallest difference is in scores that patients perceive as meaningful. Finally, measures must not only be precise but also time-effective, and could be addressed with computer-based administration. Thus, the first specific aim of the proposed study is to further establish the psychometric properties of the CPIB. This will be accomplished by: a) examining the sensitivity of the CPIB by comparing those undergoing standard HNC treatments over time with those in a stable/no treatment status; b) estimating the unit of clinically meaningful change; and c) determining relationships between scores from static short-forms with those from computerized adaptive testing (CAT). To accomplish aim 1, two groups of subjects will complete the CPIB and standard HNC outcome measures in a longitudinal study. The Treatment Group will include HNC patients currently in treatment; the Chronic Group will include individuals who are at least 5 years HNC post-treatment. It is predicted that CPIB scores will decrease over the first 3 months, but will improve and stabilize by 12 months in the Treatment group; CPIB scores will remain stable in the Chronic group. Using anchor-, distribution-based, and qualitative approaches, and clinically meaningful change scores on the CPIB will be determined. Finally, it is hypothesized that there will be strong correlations between CPIB scores derived from static and CAT-based formats. The ability to quantify communicative participation is important because it allows us to identify contributing variables whose strength may change over time. Thus, the second specific aim is to determine significant predictors of communicative participation. Treatment group subjects will provide demographics, disease/treatment-related information and psychosocial measures. It is hypothesized that CPIB will have multiple predictors, and that psychosocial factors will become stronger predictors over time. In a second study, a subgroup will complete standard speech measures to determine how traditional measures of speech predict CPIB over time. The approach is innovative because it represents a substantive departure from the status quo in HNC outcome measurement. By identifying which variables contribute to communicative participation over time, results of this study will make a significant impact on future interventio approaches based on these variables. Realization of these aims will further establish the validity of a meaningful outcome measure, identify targets for future rehabilitation, and contribute to models of functioning and disability in HNC survivors.

Public Health Relevance

One of the greatest difficulties experienced by head and neck cancer (HNC) survivors relates difficulties in verbal communication. This research is will further validate a novel communication outcomes measure, and will identify mediators of communication success. The results may lead to the identification of better treatment methods for HNC survivors whose physical, social, and psychosocial well-being is impacted by the disease and its treatment.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA177635-05
Application #
9439710
Study Section
Motor Function, Speech and Rehabilitation Study Section (MFSR)
Program Officer
Chou, Wen-Ying
Project Start
2014-04-10
Project End
2019-02-28
Budget Start
2018-03-01
Budget End
2019-02-28
Support Year
5
Fiscal Year
2018
Total Cost
Indirect Cost
Name
University of Washington
Department
Other Health Professions
Type
Schools of Arts and Sciences
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
Bolt, Susan; Baylor, Carolyn; Burns, Michael et al. (2018) ""I would have told you about being forgetful, but I forgot"": the experience of cognitive changes and communicative participation after head and neck cancer. Disabil Rehabil :1-9
Eadie, Tanya; Faust, Lauren; Bolt, Susan et al. (2018) Role of Psychosocial Factors on Communicative Participation among Survivors of Head and Neck Cancer. Otolaryngol Head Neck Surg 159:266-273
Eadie, Tanya; Kapsner-Smith, Mara; Bolt, Susan et al. (2018) Relationship between perceived social support and patient-reported communication outcomes across communication disorders: a systematic review. Int J Lang Commun Disord 53:1059-1077
Eadie, Tanya L; Otero, Devon Sawin; Bolt, Susan et al. (2016) The Effect of Noise on Relationships Between Speech Intelligibility and Self-Reported Communication Measures in Tracheoesophageal Speakers. Am J Speech Lang Pathol 25:393-407
Bolt, Susan; Eadie, Tanya; Yorkston, Kathryn et al. (2016) Variables Associated With Communicative Participation After Head and Neck Cancer. JAMA Otolaryngol Head Neck Surg 142:1145-1151
Eadie, Tanya L; Otero, Devon; Cox, Steven et al. (2016) The relationship between communicative participation and postlaryngectomy speech outcomes. Head Neck 38 Suppl 1:E1955-61