Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
2R01DA001933-10A4
Application #
2012827
Study Section
Human Development Research Subcommittee (NIDA)
Project Start
1978-09-30
Project End
1999-06-30
Budget Start
1996-09-30
Budget End
1997-06-30
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Pharmacology
Type
Schools of Medicine
DUNS #
168559177
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
Riedl, Maureen S; Schnell, Stephen A; Overland, Aaron C et al. (2009) Coexpression of alpha 2A-adrenergic and delta-opioid receptors in substance P-containing terminals in rat dorsal horn. J Comp Neurol 513:385-98
Stone, Laura S; Wilcox, George L (2004) Alpha-2-adrenergic and opioid receptor additivity in rat locus coeruleus neurons. Neurosci Lett 361:265-8
Stone, Laura S; Vulchanova, Lucy; Riedl, Maureen S et al. (2004) Effects of peripheral nerve injury on delta opioid receptor (DOR) immunoreactivity in the rat spinal cord. Neurosci Lett 361:208-11
Laughlin, Tinna M; Tram, Kevin V; Wilcox, George L et al. (2002) Comparison of antiepileptic drugs tiagabine, lamotrigine, and gabapentin in mouse models of acute, prolonged, and chronic nociception. J Pharmacol Exp Ther 302:1168-75
Fairbanks, Carolyn A; Stone, Laura S; Kitto, Kelley F et al. (2002) alpha(2C)-Adrenergic receptors mediate spinal analgesia and adrenergic-opioid synergy. J Pharmacol Exp Ther 300:282-90
Fairbanks, C A; Schreiber, K L; Brewer, K L et al. (2000) Agmatine reverses pain induced by inflammation, neuropathy, and spinal cord injury. Proc Natl Acad Sci U S A 97:10584-9
Laughlin, T M; Bethea, J R; Yezierski, R P et al. (2000) Cytokine involvement in dynorphin-induced allodynia. Pain 84:159-67
Fairbanks, C A; Nguyen, H O; Grocholski, B M et al. (2000) Moxonidine, a selective imidazoline-alpha2 -adrenergic receptor agonist, produces spinal synergistic antihyperalgesia with morphine in nerve-injured mice. Anesthesiology 93:765-73
Fairbanks, C A; Posthumus, I J; Kitto, K F et al. (2000) Moxonidine, a selective imidazoline/alpha(2) adrenergic receptor agonist, synergizes with morphine and deltorphin II to inhibit substance P-induced behavior in mice. Pain 84:13-20
Fairbanks, C A; Wilcox, G L (1999) Moxonidine, a selective alpha2-adrenergic and imidazoline receptor agonist, produces spinal antinociception in mice. J Pharmacol Exp Ther 290:403-12

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