The overall aim of the research is to further the understanding of the mental health consequences of the use of marijuana and other substances and of developmental patterns of involvement and cessation in the use of various drugs. The proposed epidemiological research is based on longitudinal data collected in adolescence and in young adulthood on a representative subsample of adolescents formerly enrolled in high school grades 10 and 11 in New York State in 1971-72. A prior adult follow-up was carried out in 1980 with 1,325 respondents 24-25 years old, 9 years after initial contact for adolescents who participated in an initial high school survey (N=1,096) and a complementary group of absentees (N=229) from the same schools. A second follow-up of the total group is planned for 1984, at ages 28-29, with field procedures identical to those followed in 1980. This proposal requests funding for reinterviewing the former regular students through personal interviews, averaging 1-1/2 hours in duration. Detailed retrospective life and drug histories will be collected as well as information from college records. Depressive symptomatology, physical health and psychological functioning will be assessed. The drugs inquired about include the following ten classes: cigarettes, alcohol, marijuana, psychedelics, heroin, other opiates, cocaine, and medical and nonmedical use of stimulants, sedatives and tranquilizers. Three activities are outlined in the proposal: (1) continued analyses of the health consequences of drug use based on the first adult follow-up in 1980, (2) implementation of the second follow-up in 1984, and (3) analyses of the additional longitudinal data. The specific objectives of the research are: (1) to examine patterns of involvement, regression, and cessation on drug use at the point in the life-cycle that spans the years from adolescence to young adulthood; (2) to identify the psychological precursors in adolescence and young adulthood of continued drug use in adulthood; (3) to specify the mental health consequences of the use of marijuana and of other drugs; (4) to investigate the interactive relationship between depressive mood and drug use from adolescence to adulthood; and (5) to identify the correlates and predictors of cessation of drug use in early adulthood.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
5R01DA003196-04
Application #
3207784
Study Section
(DACA)
Project Start
1982-06-01
Project End
1986-06-30
Budget Start
1985-05-01
Budget End
1986-06-30
Support Year
4
Fiscal Year
1985
Total Cost
Indirect Cost
Name
Columbia University (N.Y.)
Department
Type
Schools of Medicine
DUNS #
064931884
City
New York
State
NY
Country
United States
Zip Code
10027
Kandel, D B; Chen, K (2000) Types of marijuana users by longitudinal course. J Stud Alcohol 61:367-78
Chen, K; Kandel, D B (1998) Predictors of cessation of marijuana use: an event history analysis. Drug Alcohol Depend 50:109-21
Griesler, P C; Kandel, D B (1998) The impact of maternal drinking during and after pregnancy on the drinking of adolescent offspring. J Stud Alcohol 59:292-304
Chen, K; Scheier, L M; Kandel, D B (1996) Effects of chronic cocaine use on physical health: a prospective study in a general population sample. Drug Alcohol Depend 43:23-37
Chen, K; Kandel, D B (1995) The natural history of drug use from adolescence to the mid-thirties in a general population sample. Am J Public Health 85:41-7
Kandel, D B; Wu, P; Davies, M (1994) Maternal smoking during pregnancy and smoking by adolescent daughters. Am J Public Health 84:1407-13
Kandel, D B; Yamaguchi, K; Chen, K (1992) Stages of progression in drug involvement from adolescence to adulthood: further evidence for the gateway theory. J Stud Alcohol 53:447-57
Yamaguchi, K (1990) Drug use and its social covariates from the period of adolescence to young adulthood. Some implications from longitudinal studies. Recent Dev Alcohol 8:125-43
Kandel, D B; Raveis, V H (1989) Cessation of illicit drug use in young adulthood. Arch Gen Psychiatry 46:109-16
Kandel, D B; Andrews, K (1987) Processes of adolescent socialization by parents and peers. Int J Addict 22:319-42

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