This study is an epidemiologic analysis of the relationship between a potential teratogen, marihuana, pregnancy course and outcome. The effects of exposure during pregnancy will be measured both in the immediate postnatal period and during early developmental stages. The proposed design is a prospective evaluation of the experience of pregnant teenagers. Women age 18 through 20 who attend the prenatal clinic at Magee-Womens Hospital will be interviewed pre and postnatally. Babies will be examined at birth, and at 2 weeks and 8 months of age. Measures of infant outcome will include physical status, growth, infant state and development. Specific attention is focused on maternal psychological status as an important correlate of marihuana use, pregnancy outcome and infant behavior. The confounding effects of other drugs, physical status and life style of the mother will be controlled.
| Pugh, Sarah J; Richardson, Gale A; Hutcheon, Jennifer A et al. (2015) Maternal Obesity and Excessive Gestational Weight Gain Are Associated with Components of Child Cognition. J Nutr 145:2562-9 |
| Goldschmidt, Lidush; Richardson, Gale A; Willford, Jennifer et al. (2008) Prenatal marijuana exposure and intelligence test performance at age 6. J Am Acad Child Adolesc Psychiatry 47:254-63 |
| Leech, Sharon L; Larkby, Cynthia A; Day, Richard et al. (2006) Predictors and correlates of high levels of depression and anxiety symptoms among children at age 10. J Am Acad Child Adolesc Psychiatry 45:223-30 |
| Goldschmidt, L; Richardson, G A; Stoffer, D S et al. (1996) Prenatal alcohol exposure and academic achievement at age six: a nonlinear fit. Alcohol Clin Exp Res 20:763-70 |
| Richardson, G A; Day, N L; Goldschmidt, L (1995) Prenatal alcohol, marijuana, and tobacco use: infant mental and motor development. Neurotoxicol Teratol 17:479-87 |
| Day, N L; Richardson, G A; Goldschmidt, L et al. (1994) Effect of prenatal marijuana exposure on the cognitive development of offspring at age three. Neurotoxicol Teratol 16:169-75 |
| Day, N; Cornelius, M; Goldschmidt, L et al. (1992) The effects of prenatal tobacco and marijuana use on offspring growth from birth through 3 years of age. Neurotoxicol Teratol 14:407-14 |
| Richardson, G A; Day, N L (1991) Maternal and neonatal effects of moderate cocaine use during pregnancy. Neurotoxicol Teratol 13:455-60 |
| Day, N; Sambamoorthi, U; Taylor, P et al. (1991) Prenatal marijuana use and neonatal outcome. Neurotoxicol Teratol 13:329-34 |
| Robles, N; Day, N L (1990) Recall of alcohol consumption during pregnancy. J Stud Alcohol 51:403-7 |
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