Within the broad fields of social research and epidemiology, there has been much interest in the concept of vulnerability/invulnerability to various forms of physical, social, and psychological pathology. This is particularly true in the area of narcotic drug abuse, where certain individuals who grow up in """"""""high risk"""""""" environments refrain from involvement with narcotic drugs while others, similarly exposed, become readily addicted. In this connection, it has also been the case that throughout history, major public health problems have been dealt with successfully only through prevention, rather than through treatment. However, successful prevention efforts require a clear understanding of etiological mechanisms. For this reason, the proposed study seeks to provide a firmer, empirical data base from which to infer etiological mechanisms in the area of narcotic drug abuse. Previous studies have invoked socioeconomic, psychological, political, biochemical, and genetic factors as possible interacting mechanisms. The proposed study would attempt to touch on many of those areas through the use of archival, interview, and psychological test data--the latter two types to be obtained from narcotic addicts and their matched controls. Two hundred fifty male addicts would initially be involved, and these would be matched, man-for-man, with controls consisting of non-addict peers from the same neighborhood. One innovative aspect would be the additional use of peer information to provide descriptions of both addicts and controls, and by doing so, to reconstruct their social and personal developments. Subsequent data analyses would be mutivariate in scope, and extensive use of factor and path analysis is anticipated. The feasibility of such an approach has recently been demonstrated in a pilot study in which the investigators contacted and interviewed ten triads, each triad consisting of an addict, his matched control, and an informant, for a total of 30 persons interviewed.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
5R01DA003766-05
Application #
3208378
Study Section
(SRC)
Project Start
1985-04-01
Project End
1992-03-31
Budget Start
1989-05-01
Budget End
1990-03-31
Support Year
5
Fiscal Year
1989
Total Cost
Indirect Cost
Name
Friends Research Institute, Inc.
Department
Type
DUNS #
City
Baltimore
State
MD
Country
United States
Zip Code
21201
Nurco, D N; Kinlock, T W; O'Grady, K E et al. (1998) Differential contributions of family and peer factors to the etiology of narcotic addiction. Drug Alcohol Depend 51:229-37
Nurco, D N; Hanlon, T E; O'Grady, K E et al. (1997) The early emergence of narcotic addict types. Am J Drug Alcohol Abuse 23:523-42
Nurco, D N; Kinlock, T W; O'Grady, K E et al. (1996) Early family adversity as a precursor to narcotic addiction. Drug Alcohol Depend 43:103-13
Nurco, D N; Kinlock, T; O'Grady, K et al. (1996) Perceptions of social pathology in the neighborhood and the etiology of narcotic addiction. A retrospective study. J Nerv Ment Dis 184:35-42