Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
3R01DA004038-04S1
Application #
3209029
Study Section
Drug Abuse Biomedical Research Review Committee (DABR)
Project Start
1989-09-30
Project End
1992-08-31
Budget Start
1989-09-30
Budget End
1990-08-31
Support Year
4
Fiscal Year
1990
Total Cost
Indirect Cost
Name
University of Toledo
Department
Type
Schools of Medicine
DUNS #
807418939
City
Toledo
State
OH
Country
United States
Zip Code
43614
Chen, B X; Myles, J; Wilkerson, R D (1995) Role of the sympathoadrenal axis in the cardiovascular response to cocaine in conscious unrestrained rats. J Cardiovasc Pharmacol 25:817-22
Fraker Jr, T D; Temesy-Armos, P N; Brewster, P S et al. (1995) Interaction of propranolol, verapamil, and nifedipine on the myocardial depressant effect of cocaine. J Cardiovasc Pharmacol 25:579-86
Temesy-Armos, P N; Fraker Jr, T D; Brewster, P S et al. (1992) The effects of cocaine on cardiac electrophysiology in conscious, unsedated dogs. J Cardiovasc Pharmacol 19:883-91
Foy, R A; Myles, J L; Wilkerson, R D (1992) Characterization of 5-hydroxytryptamine receptors in bovine coronary arteries. J Pharmacol Exp Ther 261:601-6
Foy, R A; Myles, J L; Wilkerson, R D (1991) Contraction of bovine coronary vascular smooth muscle induced by cocaine is not mediated by norepinephrine. Life Sci 49:299-308
Wilkerson, R D; Temesy-Armos, P N; Fraker Jr, T D (1991) Pharmacokinetics and time-action profile of cocaine in dogs. NIDA Res Monogr 108:28-40
Fraker Jr, T D; Temesy-Armos, P N; Brewster, P S et al. (1990) Mechanism of cocaine-induced myocardial depression in dogs. Circulation 81:1012-6
Wilkerson, R D (1989) Cardiovascular effects of cocaine: enhancement by yohimbine and atropine. J Pharmacol Exp Ther 248:57-61
Wilkerson, R D (1988) Cardiovascular effects of cocaine in conscious dogs: importance of fully functional autonomic and central nervous systems. J Pharmacol Exp Ther 246:466-71
Wilkerson, R D (1988) Cardiovascular toxicity of cocaine. NIDA Res Monogr 88:304-24