Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
5R01DA004157-12
Application #
2117036
Study Section
Drug Abuse Biomedical Research Review Committee (DABR)
Project Start
1985-10-01
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California San Diego
Department
Psychiatry
Type
Schools of Medicine
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Cho, A K; Melega, W P; Kuczenski, R et al. (2001) Relevance of pharmacokinetic parameters in animal models of methamphetamine abuse. Synapse 39:161-6
Shilling, P D; Kelsoe, J R; Kuczenski, R et al. (2000) Differential regional zif268 messenger RNA expression in an escalating dose/binge model of amphetamine-induced psychosis. Neuroscience 96:83-90
Kuczenski, R; Segal, D S (1999) Sensitization of amphetamine-induced stereotyped behaviors during the acute response. J Pharmacol Exp Ther 288:699-709
Segal, D S; Kuczenski, R (1999) Escalating dose-binge stimulant exposure: relationship between emergent behavioral profile and differential caudate-putamen and nucleus accumbens dopamine responses. Psychopharmacology (Berl) 142:182-92
Segal, D S; Kuczenski, R (1999) Escalating dose-binge treatment with methylphenidate: role of serotonin in the emergent behavioral profile. J Pharmacol Exp Ther 291:19-30
Kuczenski, R; Segal, D S (1999) Dynamic changes in sensitivity occur during the acute response to cocaine and methylphenidate. Psychopharmacology (Berl) 147:96-103
Kuczenski, R; Segal, D S (1999) Sensitization of amphetamine-induced stereotyped behaviors during the acute response: role of D1 and D2 dopamine receptors. Brain Res 822:164-74
Cho, A K; Melega, W P; Kuczenski, R et al. (1999) Caudate-putamen dopamine and stereotypy response profiles after intravenous and subcutaneous amphetamine. Synapse 31:125-33
Segal, D S; Kuczenski, R (1997) Behavioral alterations induced by an escalating dose-binge pattern of cocaine administration. Behav Brain Res 88:251-60
Conti, L H; Segal, D S; Kuczenski, R (1997) Maintenance of amphetamine-induced stereotypy and locomotion requires ongoing dopamine receptor activation. Psychopharmacology (Berl) 130:183-8

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