Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
5R01DA004190-02
Application #
3209478
Study Section
(DABA)
Project Start
1987-02-01
Project End
1990-01-31
Budget Start
1988-02-01
Budget End
1989-01-31
Support Year
2
Fiscal Year
1988
Total Cost
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Type
Schools of Veterinary Medicine
DUNS #
168559177
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
Larson, A A; Yukhananov, R Y; Kreeger, J S (1995) Enhanced N-methyl-D-aspartate (NMDA)-induced activity following morphine: sensitivity to sigma and PCP ligands. NIDA Res Monogr 147:146-60
Larson, A A; Kitto, K F (1995) Sensitization to the behavioral effect of kainic acid in the mouse is mediated by nitric oxide. J Pharmacol Exp Ther 275:544-50
Goettl, V M; Larson, A A (1994) Activity at phencyclidine and mu opioid sites mediates the hyperalgesic and antinociceptive properties of the N-terminus of substance P in a model of visceral pain. Neuroscience 60:375-82
Yukhananov RYu; Larson, A A (1994) Involvement of NMDA receptors in naloxone-induced contractions of the isolated guinea pig ileum after preincubation with morphine. J Pharmacol Exp Ther 271:1365-70
Hornfeldt, C S; Sun, X; Larson, A A (1994) The NH2-terminus of substance P modulates NMDA-induced activity in the mouse spinal cord. J Neurosci 14:3364-9
Yukhananov RYu; Larson, A A (1994) Morphine modulates excitatory amino acid-induced activity in the mouse spinal cord: short-term effects on N-methyl-D-aspartate (NMDA) and long-term effects on kainic acid. Brain Res 646:194-200
Mousseau, D D; Sun, X; Larson, A A (1994) An antinociceptive effect of capsaicin in the adult mouse mediated by the NH2-terminus of substance P. J Pharmacol Exp Ther 268:785-90
Kovacs, K J; Larson, A A (1994) Density of NMDA-coupled and uncoupled 1-[1-(2-[3H]thienyl) cyclohexyl]piperidine recognition sites in the brain and spinal cord: differential effects of NMDA agonists and antagonists. J Neurochem 63:1757-65
Mousseau, D D; Larson, A A (1994) Substance P analogs displace sigma binding differentially in the brain and spinal cord of the adult mouse. Metab Brain Dis 9:249-55
Larson, A A; Sun, X (1994) Role of the NH2-terminus of substance P in the inhibition by capsaicin of behavioral sensitization to kainic acid-induced activity in the adult mouse. J Pharmacol Exp Ther 268:366-71

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