Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
5R01DA004953-08
Application #
2117343
Study Section
Drug Abuse Biomedical Research Review Committee (DABR)
Project Start
1988-04-01
Project End
1997-07-31
Budget Start
1995-08-01
Budget End
1997-07-31
Support Year
8
Fiscal Year
1995
Total Cost
Indirect Cost

  Institution

Name
Henry M. Jackson Fdn for the Adv Mil/Med
Department
Type
DUNS #
City
Rockville
State
MD
Country
United States
Zip Code
20817

  Publications

Romualdi, P; D'Addario, C; Ferri, S et al. (2001) Chronic GBR 12909 administration differentially alters prodynorphin gene expression compared to cocaine. Eur J Pharmacol 413:207-12
Azaryan, A V; Clock, B J; Rosenberger, J G et al. (1998) Transient upregulation of mu opioid receptor mRNA levels in nucleus accumbens during chronic cocaine administration. Can J Physiol Pharmacol 76:278-83
Noble, F; Cox, B M (1997) The role of dopaminergic systems in opioid receptor desensitization in nucleus accumbens and caudate putamen of rat after chronic morphine treatment. J Pharmacol Exp Ther 283:557-65
Buzas, B; Rosenberger, J; Cox, B M (1996) Mu and delta opioid receptor gene expression after chronic treatment with opioid agonist. Neuroreport 7:1505-8
Noble, F; Cox, B M (1996) Differences among mouse strains in the regulation by mu, delta 1 and delta 2 opioid receptors of striatal adenylyl cyclases activated by dopamine D1 or adenosine A2a receptors. Brain Res 716:107-17
Noble, F; Cox, B M (1996) Differential desensitization of mu- and delta- opioid receptors in selected neural pathways following chronic morphine treatment. Br J Pharmacol 117:161-9
Noble, F; Cox, B M (1995) Differential regulation of D1 dopamine receptor- and of A2a adenosine receptor-stimulated adenylyl cyclase by mu-, delta 1-, and delta 2-opioid agonists in rat caudate putamen. J Neurochem 65:125-33
Unterwald, E M; Cox, B M; Kreek, M J et al. (1993) Chronic repeated cocaine administration alters basal and opioid-regulated adenylyl cyclase activity. Synapse 15:33-8