Abstract

The overall goals of this project are to develop and test reliable, valid methods for detecting drug abusers, characterizing drug use severity and subtyping drug abusers in clinically useful ways. Because the first four years of this project have run concurrently with the DSM-IV revision process, we have focused on issues directly related to suggested revisions and we have met our targeted goals for data collection. In the renewal period, we propose to complete and extend data analyses originally planned and to focus new data collection on one promising aspect of diagnosing drug abusers: psychiatric comorbidity, specifically DSM-III-R/DSM-IV Axis II (Personality) disorders. In the renewal period we propose to 1. Extend data analyses, particularly in the areas of characterizing drug use severity and screening for drug abuse, 2. Give a comprehensive battery of assessments to determine rates of Personality Disorders and their clinical correlates in a. a variety of clinical samples of substance abusers and b. demographically matched community controls, 3. Assess several aspects of reliability and validity of differing systems and methods for diagnosing Personality Disorders/Dimensions in substance abusers, 4. Apply and evaluate methods to enhance the reliability and validity of existing instruments for diagnosing Personality Disorders/Dimensions in substance abusers, and 5. Evaluate the associations among different Personality Disorders in substance abusers and seek underlying dimensions of personality pathology in this special population.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
5R01DA005592-07
Application #
2117915
Study Section
Drug Abuse Clinical and Behavioral Research Review Committee (DACB)
Project Start
1988-08-01
Project End
1996-06-30
Budget Start
1994-08-01
Budget End
1995-06-30
Support Year
7
Fiscal Year
1994
Total Cost
Indirect Cost

  Institution

Name
Apt Foundation, Inc.
Department
Type
DUNS #
City
New Haven
State
CT
Country
United States
Zip Code
06511

  Publications

Samuel, Douglas B; Carroll, Kathleen M; Rounsaville, Bruce J et al. (2013) Personality disorders as maladaptive, extreme variants of normal personality: borderline personality disorder and neuroticism in a substance using sample. J Pers Disord 27:625-35
Hernandez-Avila, Carlos A; Rounsaville, Bruce J; Kranzler, Henry R (2004) Opioid-, cannabis- and alcohol-dependent women show more rapid progression to substance abuse treatment. Drug Alcohol Depend 74:265-72
Ball, S A; Rounsaville, B J; Tennen, H et al. (2001) Reliability of personality disorder symptoms and personality traits in substance-dependent inpatients. J Abnorm Psychol 110:341-52
Verheul, R; Kranzler, H R; Poling, J et al. (2000) Co-occurrence of Axis I and Axis II disorders in substance abusers. Acta Psychiatr Scand 101:110-8
Verheul, R; Kranzler, H R; Poling, J et al. (2000) Axis I and Axis II disorders in alcoholics and drug addicts: fact or artifact? J Stud Alcohol 61:101-10
Poling, J; Rounsaville, B J; Ball, S et al. (1999) Rates of personality disorders in substance abusers: a comparison between DSM-III-R and DSM-IV. J Pers Disord 13:375-84
Cecero, J J; Ball, S A; Tennen, H et al. (1999) Concurrent and predictive validity of antisocial personality disorder subtyping among substance abusers. J Nerv Ment Dis 187:478-86
Rounsaville, B J; Kranzler, H R; Ball, S et al. (1998) Personality disorders in substance abusers: relation to substance use. J Nerv Ment Dis 186:87-95
Ball, S A; Kranzler, H R; Tennen, H et al. (1998) Personality disorder and dimension differences between type A and type B substance abusers. J Pers Disord 12:1-12
Skipsey, K; Burleson, J A; Kranzler, H R (1997) Utility of the AUDIT for identification of hazardous or harmful drinking in drug-dependent patients. Drug Alcohol Depend 45:157-63

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