Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
2R01DA006305-07A1
Application #
2013024
Study Section
Human Development Research Subcommittee (NIDA)
Project Start
1989-09-30
Project End
1999-08-31
Budget Start
1996-09-25
Budget End
1997-08-31
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Georgia Institute of Technology
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
097394084
City
Atlanta
State
GA
Country
United States
Zip Code
30332

  Publications

Misra, Milind; Shi, Qing; Ye, Xiaocong et al. (2010) Quantitative structure-activity relationship studies of threo-methylphenidate analogs. Bioorg Med Chem 18:7221-38
Kim, Deog-Il; Deutsch, Howard M; Ye, Xiaocong et al. (2007) Synthesis and pharmacology of site-specific cocaine abuse treatment agents: restricted rotation analogues of methylphenidate. J Med Chem 50:2718-31
Kim, Deog-Il; Schweri, Margaret M; Deutsch, Howard M (2003) Synthesis and pharmacology of site specific cocaine abuse treatment agents: 8-substituted isotropane (3-azabicyclo[3.2.1]octane) dopamine uptake inhibitors. J Med Chem 46:1456-64
Schweri, M M; Deutsch, H M; Massey, A T et al. (2002) Biochemical and behavioral characterization of novel methylphenidate analogs. J Pharmacol Exp Ther 301:527-35
Deutsch, H M; Ye, X; Shi, Q et al. (2001) Synthesis and pharmacology of site specific cocaine abuse treatment agents: a new synthetic methodology for methylphenidate analogs based on the Blaise reaction. Eur J Med Chem 36:303-11
Wayment, H K; Deutsch, H; Schweri, M M et al. (1999) Effects of methylphenidate analogues on phenethylamine substrates for the striatal dopamine transporter: potential as amphetamine antagonists? J Neurochem 72:1266-74
Deutsch, H M; Collard, D M; Zhang, L et al. (1999) Synthesis and pharmacology of site-specific cocaine abuse treatment agents: 2-(aminomethyl)-3-phenylbicyclo[2.2.2]- and -[2.2.1]alkane dopamine uptake inhibitors. J Med Chem 42:882-95
Javanmard, S; Deutsch, H M; Collard, D M et al. (1999) Synthesis and pharmacology of site-specific cocaine abuse treatment agents: 2-substituted-6-amino-5-phenylbicyclo[2.2.2]octanes. J Med Chem 42:4836-43
Schweri, M M; de Costa, B R; Rice, K C (1998) Fourphit, an acylating phencyclidine derivative, attenuates cocaine-induced hyperactivity in rats. Pharmacol Biochem Behav 60:615-23
Deutsch, H M; Shi, Q; Gruszecka-Kowalik, E et al. (1996) Synthesis and pharmacology of potential cocaine antagonists. 2. Structure-activity relationship studies of aromatic ring-substituted methylphenidate analogs. J Med Chem 39:1201-9

Showing the most recent 10 out of 13 publications