Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
2R01DA007415-04A2
Application #
2119925
Study Section
Special Emphasis Panel (SRCD (22))
Project Start
1991-09-30
Project End
2001-01-31
Budget Start
1996-05-01
Budget End
1997-01-31
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Oregon Health and Science University
Department
Type
Organized Research Units
DUNS #
009584210
City
Portland
State
OR
Country
United States
Zip Code
97239
Benson, C J; Sutherland, S P (2001) Toward an understanding of the molecules that sense myocardial ischemia. Ann N Y Acad Sci 940:96-109
Benson, C J; Eckert, S P; McCleskey, E W (1999) Acid-evoked currents in cardiac sensory neurons: A possible mediator of myocardial ischemic sensation. Circ Res 84:921-8
Cook, S P; McCleskey, E W (1997) Desensitization, recovery and Ca(2+)-dependent modulation of ATP-gated P2X receptors in nociceptors. Neuropharmacology 36:1303-8
Ingram, S; Wilding, T J; McCleskey, E W et al. (1997) Efficacy and kinetics of opioid action on acutely dissociated neurons. Mol Pharmacol 52:136-43
Wilding, T J; Womack, M D; McCleskey, E W (1995) Fast, local signal transduction between the mu opioid receptor and Ca2+ channels. J Neurosci 15:4124-32
Nah, S Y; Park, H J; McCleskey, E W (1995) A trace component of ginseng that inhibits Ca2+ channels through a pertussis toxin-sensitive G protein. Proc Natl Acad Sci U S A 92:8739-43
Womack, M D; McCleskey, E W (1995) Interaction of opioids and membrane potential to modulate Ca2+ channels in rat dorsal root ganglion neurons. J Neurophysiol 73:1793-8
Nah, S Y; McCleskey, E W (1994) Ginseng root extract inhibits calcium channels in rat sensory neurons through a similar path, but different receptor, as mu-type opioids. J Ethnopharmacol 42:45-51
McCleskey, E W (1994) Calcium channels: cellular roles and molecular mechanisms. Curr Opin Neurobiol 4:304-12
Akins, P T; McCleskey, E W (1993) Characterization of potassium currents in adult rat sensory neurons and modulation by opioids and cyclic AMP. Neuroscience 56:759-69

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