Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
3R01DA008098-02S1
Application #
2764146
Study Section
Human Development Research Subcommittee (NIDA)
Project Start
1997-04-10
Project End
2000-02-29
Budget Start
1998-04-15
Budget End
1999-02-28
Support Year
2
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Medical College of Wisconsin
Department
Pharmacology
Type
Schools of Medicine
DUNS #
073134603
City
Milwaukee
State
WI
Country
United States
Zip Code
53226
Muthian, S; Rademacher, D J; Roelke, C T et al. (2004) Anandamide content is increased and CB1 cannabinoid receptor blockade is protective during transient, focal cerebral ischemia. Neuroscience 129:743-50
Patel, S; Hillard, C J (2001) Cannabinoid CB(1) receptor agonists produce cerebellar dysfunction in mice. J Pharmacol Exp Ther 297:629-37
Nogueron, M I; Porgilsson, B; Schneider, W E et al. (2001) Cannabinoid receptor agonists inhibit depolarization-induced calcium influx in cerebellar granule neurons. J Neurochem 79:371-81
Hillard, C J (2000) Endocannabinoids and vascular function. J Pharmacol Exp Ther 294:27-32
Jarrahian, A; Manna, S; Edgemond, W S et al. (2000) Structure-activity relationships among N-arachidonylethanolamine (Anandamide) head group analogues for the anandamide transporter. J Neurochem 74:2597-606
Hillard, C J (2000) Biochemistry and pharmacology of the endocannabinoids arachidonylethanolamide and 2-arachidonylglycerol. Prostaglandins Other Lipid Mediat 61:18-Mar
Kearn, C S; Greenberg, M J; DiCamelli, R et al. (1999) Relationships between ligand affinities for the cerebellar cannabinoid receptor CB1 and the induction of GDP/GTP exchange. J Neurochem 72:2379-87
Hillard, C J; Muthian, S; Kearn, C S (1999) Effects of CB(1) cannabinoid receptor activation on cerebellar granule cell nitric oxide synthase activity. FEBS Lett 459:277-81
Hillard, C J; Campbell, W B (1997) Biochemistry and pharmacology of arachidonylethanolamide, a putative endogenous cannabinoid. J Lipid Res 38:2383-98