Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
5R01DA008379-03
Application #
2120862
Study Section
Drug Abuse Biomedical Research Review Committee (DABR)
Program Officer
Lin, Geraline
Project Start
1994-08-15
Project End
1998-11-30
Budget Start
1996-07-01
Budget End
1997-11-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Illinois at Chicago
Department
Other Basic Sciences
Type
Schools of Medicine
DUNS #
121911077
City
Chicago
State
IL
Country
United States
Zip Code
60612
Nyola, Ajeeta; Karpowich, Nathan K; Zhen, Juan et al. (2010) Substrate and drug binding sites in LeuT. Curr Opin Struct Biol 20:415-22
Reith, M E A; Zhen, J; Chen, N (2006) The importance of company: Na+ and Cl- influence substrate interaction with SLC6 transporters and other proteins. Handb Exp Pharmacol :75-93
Zhen, Juan; Chen, Nianhang; Reith, Maarten E A (2005) Differences in interactions with the dopamine transporter as revealed by diminishment of Na(+) gradient and membrane potential: dopamine versus other substrates. Neuropharmacology 49:769-79
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Wang, Lijuan C; Cui, Xiao-Nan; Chen, Nianhang et al. (2003) Binding of cocaine-like radioligands to the dopamine transporter at 37 degrees C: effect of Na+ and substrates. J Neurosci Methods 131:27-33
Chen, Nianhang; Rickey, Judy; Reith, Maarten E A (2003) Na+ stimulates binding of dopamine to the dopamine transporter in cells but not in cell-free preparations. J Neurochem 86:678-86
Wu, Qun; Reith, Maarten E A; Walker, Q David et al. (2002) Concurrent autoreceptor-mediated control of dopamine release and uptake during neurotransmission: an in vivo voltammetric study. J Neurosci 22:6272-81

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