Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
5R01DA009094-03
Application #
2122074
Study Section
Drug Abuse Biomedical Research Review Committee (DABR)
Project Start
1994-09-01
Project End
1999-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Mount Sinai School of Medicine
Department
Anesthesiology
Type
Schools of Medicine
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10029
Berg, Kelly A; Evans, Kenda L J; Cropper, Jodie D et al. (2003) Temporal regulation of agonist efficacy at 5-hydroxytryptamine (5-HT)1A and 5-HT 1B receptors. J Pharmacol Exp Ther 304:200-5
Stout, Brian D; Clarke, William P; Berg, Kelly A (2002) Rapid desensitization of the serotonin(2C) receptor system: effector pathway and agonist dependence. J Pharmacol Exp Ther 302:957-62
Evans, K L; Cropper, J D; Berg, K A et al. (2001) Mechanisms of regulation of agonist efficacy at the 5-HT(1A) receptor by phospholipid-derived signaling components. J Pharmacol Exp Ther 297:1025-35
Berg, K A; Stout, B D; Maayani, S et al. (2001) Differences in rapid desensitization of 5-hydroxytryptamine2A and 5-hydroxytryptamine2C receptor-mediated phospholipase C activation. J Pharmacol Exp Ther 299:593-602
Cherstniakova, S A; Bi, D; Fuller, D R et al. (2001) Metabolism of vanoxerine, 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine, by human cytochrome P450 enzymes. Drug Metab Dispos 29:1216-20
Berg, K A; Cropper, J D; Niswender, C M et al. (2001) RNA-editing of the 5-HT(2C) receptor alters agonist-receptor-effector coupling specificity. Br J Pharmacol 134:386-92
Berg, K A; Stout, B D; Cropper, J D et al. (1999) Novel actions of inverse agonists on 5-HT2C receptor systems. Mol Pharmacol 55:863-72
Scalzitti, J M; Berg, K A; Kratowicz, S A et al. (1998) Regulation of serotonin2A receptor expression by an antisense oligodeoxynucleotide. J Neurochem 71:1457-63
Berg, K A; Maayani, S; Goldfarb, J et al. (1998) Effector pathway-dependent relative efficacy at serotonin type 2A and 2C receptors: evidence for agonist-directed trafficking of receptor stimulus. Mol Pharmacol 54:94-104
Berg, K A; Maayani, S; Clarke, W P (1996) 5-hydroxytryptamine2C receptor activation inhibits 5-hydroxytryptamine1B-like receptor function via arachidonic acid metabolism. Mol Pharmacol 50:1017-23

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