Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
5R01DA009462-03
Application #
2122717
Study Section
Special Emphasis Panel (SRCD)
Project Start
1994-09-30
Project End
1999-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Harvard University
Department
Type
Schools of Medicine
DUNS #
082359691
City
Boston
State
MA
Country
United States
Zip Code
02115
Meltzer, Peter C; Blundell, Paul; Zona, Thomas et al. (2003) A second-generation 99m technetium single photon emission computed tomography agent that provides in vivo images of the dopamine transporter in primate brain. J Med Chem 46:3483-96
Madras, Bertha K; Fahey, Michele A; Miller, Gregory M et al. (2003) Non-amine-based dopamine transporter (reuptake) inhibitors retain properties of amine-based progenitors. Eur J Pharmacol 479:41-51
Meschler, J P; Howlett, A C; Madras, B K (2001) Cannabinoid receptor agonist and antagonist effects on motor function in normal and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP)-treated non-human primates. Psychopharmacology (Berl) 156:79-85
Miller, G M; Yatin, S M; De La Garza 2nd, R et al. (2001) Cloning of dopamine, norepinephrine and serotonin transporters from monkey brain: relevance to cocaine sensitivity. Brain Res Mol Brain Res 87:124-43
Goulet, M; Madras, B K (2000) D(1) dopamine receptor agonists are more effective in alleviating advanced than mild parkinsonism in 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine-treated monkeys. J Pharmacol Exp Ther 292:714-24
Meltzer, P C; Blundell, P; Huang, H et al. (2000) 3-Aryl-2-carbomethoxybicyclo[3.2.1]oct-2-enes inhibit WIN 35,428 binding potently and selectively at the dopamine transporter. Bioorg Med Chem 8:581-90
De La Garza 2nd, R; Madras, B K (2000) [(3)H]PNU-101958, a D(4) dopamine receptor probe, accumulates in prefrontal cortex and hippocampus of non-human primate brain. Synapse 37:232-44
Morris, E D; Bonab, A A; Alpert, N M et al. (1999) Concentration of dopamine transporters: to Bmax or not to Bmax? Synapse 32:136-40
Madras, B K; Gracz, L M; Meltzer, P C et al. (1998) Altropane, a SPECT or PET imaging probe for dopamine neurons: II. Distribution to dopamine-rich regions of primate brain. Synapse 29:105-15
Madras, B K; Meltzer, P C; Liang, A Y et al. (1998) Altropane, a SPECT or PET imaging probe for dopamine neurons: I. Dopamine transporter binding in primate brain. Synapse 29:93-104

Showing the most recent 10 out of 13 publications