Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
1R01DA009978-01A1
Application #
2123427
Study Section
Human Development Research Subcommittee (NIDA)
Project Start
1996-09-30
Project End
2000-08-31
Budget Start
1996-09-30
Budget End
1997-08-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Virginia Commonwealth University
Department
Pharmacology
Type
Schools of Medicine
DUNS #
City
Richmond
State
VA
Country
United States
Zip Code
23298
Soroceanu, Liliana; Murase, Ryuichi; Limbad, Chandani et al. (2013) Id-1 is a key transcriptional regulator of glioblastoma aggressiveness and a novel therapeutic target. Cancer Res 73:1559-69
McAllister, Sean D; Murase, Ryuichi; Christian, Rigel T et al. (2011) Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasis. Breast Cancer Res Treat 129:37-47
Zhao, Pingwei; Leonoudakis, Dmitri; Abood, Mary E et al. (2010) Cannabinoid receptor activation reduces TNFalpha-induced surface localization of AMPAR-type glutamate receptors and excitotoxicity. Neuropharmacology 58:551-8
Scotter, Emma L; Abood, Mary E; Glass, Michelle (2010) The endocannabinoid system as a target for the treatment of neurodegenerative disease. Br J Pharmacol 160:480-98
Marcu, Jahan P; Christian, Rigel T; Lau, Darryl et al. (2010) Cannabidiol enhances the inhibitory effects of delta9-tetrahydrocannabinol on human glioblastoma cell proliferation and survival. Mol Cancer Ther 9:180-9
Kapur, Ankur; Samaniego, Patrick; Thakur, Ganesh A et al. (2008) Mapping the structural requirements in the CB1 cannabinoid receptor transmembrane helix II for signal transduction. J Pharmacol Exp Ther 325:341-8
McAllister, Sean D; Christian, Rigel T; Horowitz, Maxx P et al. (2007) Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells. Mol Cancer Ther 6:2921-7
Anavi-Goffer, Sharon; Fleischer, Daniel; Hurst, Dow P et al. (2007) Helix 8 Leu in the CB1 cannabinoid receptor contributes to selective signal transduction mechanisms. J Biol Chem 282:25100-13
Kapur, Ankur; Hurst, Dow P; Fleischer, Daniel et al. (2007) Mutation studies of Ser7.39 and Ser2.60 in the human CB1 cannabinoid receptor: evidence for a serine-induced bend in CB1 transmembrane helix 7. Mol Pharmacol 71:1512-24
Gehani, Neal C; Nalwalk, Julia W; Razdan, Raj K et al. (2007) Significance of cannabinoid CB1 receptors in improgan antinociception. J Pain 8:850-60

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