Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
1R01DA010045-01A1
Application #
2123506
Study Section
Human Development Research Subcommittee (NIDA)
Project Start
1996-09-01
Project End
2000-07-31
Budget Start
1996-09-01
Budget End
1997-07-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Medical College of Georgia (MCG)
Department
Biochemistry
Type
Schools of Medicine
DUNS #
City
Augusta
State
GA
Country
United States
Zip Code
30912
Inoue, Katsuhisa; Fei, You-Jun; Huang, Wei et al. (2002) Functional identity of Drosophila melanogaster Indy as a cation-independent, electroneutral transporter for tricarboxylic acid-cycle intermediates. Biochem J 367:313-9
Hatanaka, T; Huang, W; Ling, R et al. (2001) Evidence for the transport of neutral as well as cationic amino acids by ATA3, a novel and liver-specific subtype of amino acid transport system A. Biochim Biophys Acta 1510:10-7
Seth, P; Ganapathy, M E; Conway, S J et al. (2001) Expression pattern of the type 1 sigma receptor in the brain and identity of critical anionic amino acid residues in the ligand-binding domain of the receptor. Biochim Biophys Acta 1540:59-67
Nakanishi, T; Kekuda, R; Fei, Y J et al. (2001) Cloning and functional characterization of a new subtype of the amino acid transport system N. Am J Physiol Cell Physiol 281:C1757-68
Ganapathy, V; Prasad, P D; Ganapathy, M E et al. (2000) Placental transporters relevant to drug distribution across the maternal-fetal interface. J Pharmacol Exp Ther 294:413-20
Huang, W; Wang, H; Kekuda, R et al. (2000) Transport of N-acetylaspartate by the Na(+)-dependent high-affinity dicarboxylate transporter NaDC3 and its relevance to the expression of the transporter in the brain. J Pharmacol Exp Ther 295:392-403
Wu, X; Huang, W; Ganapathy, M E et al. (2000) Structure, function, and regional distribution of the organic cation transporter OCT3 in the kidney. Am J Physiol Renal Physiol 279:F449-58
Sugawara, M; Nakanishi, T; Fei, Y J et al. (2000) Cloning of an amino acid transporter with functional characteristics and tissue expression pattern identical to that of system A. J Biol Chem 275:16473-7
Kekuda, R; Leibach, F H; Furesz, T C et al. (2000) Polarized distribution of interleukin-1 receptors and their role in regulation of serotonin transporter in placenta. J Pharmacol Exp Ther 292:1032-41
Rajan, D P; Huang, W; Kekuda, R et al. (2000) Differential influence of the 4F2 heavy chain and the protein related to b(0,+) amino acid transport on substrate affinity of the heteromeric b(0,+) amino acid transporter. J Biol Chem 275:14331-5

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