Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
1R01DA010275-01
Application #
2123730
Study Section
Special Emphasis Panel (SRCD (48))
Project Start
1996-06-20
Project End
2000-03-31
Budget Start
1996-06-20
Budget End
1997-03-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Maryland Baltimore
Department
Dentistry
Type
Schools of Dentistry
DUNS #
003255213
City
Baltimore
State
MD
Country
United States
Zip Code
21201
Ren, Ke; Dubner, Ronald (2007) Pain facilitation and activity-dependent plasticity in pain modulatory circuitry: role of BDNF-TrkB signaling and NMDA receptors. Mol Neurobiol 35:224-35
Guo, Wei; Wang, Hu; Watanabe, Mineo et al. (2007) Glial-cytokine-neuronal interactions underlying the mechanisms of persistent pain. J Neurosci 27:6006-18
Guo, Wei; Robbins, Meredith T; Wei, Feng et al. (2006) Supraspinal brain-derived neurotrophic factor signaling: a novel mechanism for descending pain facilitation. J Neurosci 26:126-37
Dubner, Ronald; Ren, Ke (2004) Brainstem mechanisms of persistent pain following injury. J Orofac Pain 18:299-305
Anseloni, V; Ren, K; Dubner, R et al. (2004) Ontogeny of analgesia elicited by non-nutritive suckling in acute and persistent neonatal rat pain models. Pain 109:507-13
Guan, Yun; Guo, Wei; Robbins, Meredith T et al. (2004) Changes in AMPA receptor phosphorylation in the rostral ventromedial medulla after inflammatory hyperalgesia in rats. Neurosci Lett 366:201-5
Guo, Wei; Wei, Feng; Zou, Shiping et al. (2004) Group I metabotropic glutamate receptor NMDA receptor coupling and signaling cascade mediate spinal dorsal horn NMDA receptor 2B tyrosine phosphorylation associated with inflammatory hyperalgesia. J Neurosci 24:9161-73
Guan, Yun; Guo, Wei; Zou, Shi-Ping et al. (2003) Inflammation-induced upregulation of AMPA receptor subunit expression in brain stem pain modulatory circuitry. Pain 104:401-13
Guo, Wei; Zou, Shiping; Tal, Michael et al. (2002) Activation of spinal kainate receptors after inflammation: behavioral hyperalgesia and subunit gene expression. Eur J Pharmacol 452:309-18
Terayama, R; Dubner, R; Ren, K (2002) The roles of NMDA receptor activation and nucleus reticularis gigantocellularis in the time-dependent changes in descending inhibition after inflammation. Pain 97:171-81

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