Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
1R01DA010480-01
Application #
2123901
Study Section
Human Development Research Subcommittee (NIDA)
Project Start
1996-09-01
Project End
1997-06-30
Budget Start
1996-09-01
Budget End
1997-06-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Brigham and Women's Hospital
Department
Type
DUNS #
071723621
City
Boston
State
MA
Country
United States
Zip Code
02115
Katz, Joel T; Shannon, Richard P (2006) Bacteria and coronary atheroma: more fingerprints but no smoking gun. Circulation 113:920-2
Zhao, Tingcun; Parikh, Pratik; Bhashyam, Siva et al. (2006) Direct effects of glucagon-like peptide-1 on myocardial contractility and glucose uptake in normal and postischemic isolated rat hearts. J Pharmacol Exp Ther 317:1106-13
Parikh, Pratik; Nikolaidis, Lazaros A; Stolarski, Carol et al. (2005) Chronic exposure to cocaine binging predisposes to an accelerated course of dilated cardiomyopathy in conscious dogs following rapid ventricular pacing. J Pharmacol Exp Ther 315:1013-9
Nikolaidis, Lazaros A; Elahi, Dariush; Shen, You-Tang et al. (2005) Active metabolite of GLP-1 mediates myocardial glucose uptake and improves left ventricular performance in conscious dogs with dilated cardiomyopathy. Am J Physiol Heart Circ Physiol 289:H2401-8
Nikolaidis, Lazaros A; Mathier, Michael A; Doverspike, Aaron et al. (2005) Coronary blood flow responses are impaired independent of NO and endothelial function in conscious dogs with dilated cardiomyopathy. J Card Fail 11:313-21
Nikolaidis, Lazaros A; Trumble, Dennis; Hentosz, Teresa et al. (2004) Catecholamines restore myocardial contractility in dilated cardiomyopathy at the expense of increased coronary blood flow and myocardial oxygen consumption (MvO2 cost of catecholamines in heart failure). Eur J Heart Fail 6:409-19
Nikolaidis, Lazaros A; Sturzu, Anthony; Stolarski, Carol et al. (2004) The development of myocardial insulin resistance in conscious dogs with advanced dilated cardiomyopathy. Cardiovasc Res 61:297-306
Nikolaidis, Lazaros A; Elahi, Dariush; Hentosz, Teresa et al. (2004) Recombinant glucagon-like peptide-1 increases myocardial glucose uptake and improves left ventricular performance in conscious dogs with pacing-induced dilated cardiomyopathy. Circulation 110:955-61
Nikolaidis, Lazaros A; Doverspike, Aaron; Huerbin, Rhonda et al. (2002) Angiotensin-converting enzyme inhibitors improve coronary flow reserve in dilated cardiomyopathy by a bradykinin-mediated, nitric oxide-dependent mechanism. Circulation 105:2785-90
Mathier, Michael A; Shen, You-Tang; Shannon, Richard P (2002) Exaggerated cardiovascular effects of cocaine in conscious dogs with pacing-induced dilated cardiomyopathy. J Card Fail 8:407-15

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