Systemically Administered Dynorphins

Butelman, Eduardo R.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute on Drug Abuse (NIDA)
• Type: Research Project (R01)
• Project #: 1R01DA011113-01
• Application #: 2014159
• Study Section: Special Emphasis Panel (SRCD (27))
• Project Start: 1996-09-29
• Project End: 1999-07-31
• Budget Start: 1996-09-29
• Budget End: 1997-07-31
• Support Year: 1
• Fiscal Year: 1996

Institution

• Name: Rockefeller University
• Department: Biology
• Type: Other Domestic Higher Education
• DUNS #: 071037113
• City: New York
• State: NY
• Country: United States
• Zip Code: 10065

Publications

Lovell, Kimberly M; Vasiljevik, Tamara; Araya, Juan J et al. (2012) Semisynthetic neoclerodanes as kappa opioid receptor probes. Bioorg Med Chem 20:3100-10

Kreek, M J; Schlussman, S D; Reed, B et al. (2009) Bidirectional translational research: Progress in understanding addictive diseases. Neuropharmacology 56 Suppl 1:32-43

Schmidt, Mark S; Prisinzano, Thomas E; Tidgewell, Kevin et al. (2005) Determination of Salvinorin A in body fluids by high performance liquid chromatography-atmospheric pressure chemical ionization. J Chromatogr B Analyt Technol Biomed Life Sci 818:221-5

Schmidt, Matthew D; Schmidt, Mark S; Butelman, Eduardo R et al. (2005) Pharmacokinetics of the plant-derived kappa-opioid hallucinogen salvinorin A in nonhuman primates. Synapse 58:208-10

Butelman, Eduardo R; Harris, Todd J; Kreek, Mary Jeanne (2004) Antiallodynic effects of loperamide and fentanyl against topical capsaicin-induced allodynia in unanesthetized primates. J Pharmacol Exp Ther 311:155-63

Butelman, Eduardo R; Ball, Jonathan W; Kreek, Mary-Jeanne (2004) Peripheral selectivity and apparent efficacy of dynorphins: comparison to non-peptidic kappa-opioid agonists in rhesus monkeys. Psychoneuroendocrinology 29:307-26

Butelman, Eduardo R; Harris, Todd J; Kreek, Mary Jeanne (2004) The plant-derived hallucinogen, salvinorin A, produces kappa-opioid agonist-like discriminative effects in rhesus monkeys. Psychopharmacology (Berl) 172:220-4

Butelman, Eduardo R; Ball, Jonathan W; Harris, Todd J et al. (2003) Topical capsaicin-induced allodynia in unanesthetized primates: pharmacological modulation. J Pharmacol Exp Ther 306:1106-14

Butelman, Eduardo R; Ball, Jonathan W; Kreek, Mary-Jeanne (2002) Comparison of the discriminative and neuroendocrine effects of centrally penetrating kappa-opioid agonists in rhesus monkeys. Psychopharmacology (Berl) 164:115-20

Mathieu-Kia, A M; Kellogg, S H; Butelman, E R et al. (2002) Nicotine addiction: insights from recent animal studies. Psychopharmacology (Berl) 162:102-18