Cardiotoxicity After Maternal Cocaine Exposure

Sun, Lena S.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute on Drug Abuse (NIDA)
• Type: Research Project (R01)
• Project #: 5R01DA012962-04
• Application #: 6624763
• Study Section: Surgery, Anesthesiology and Trauma Study Section (SAT)
• Program Officer: Thadani, Pushpa
• Project Start: 2000-01-01
• Project End: 2004-11-30
• Budget Start: 2002-12-01
• Budget End: 2003-11-30
• Support Year: 4
• Fiscal Year: 2003
• Total Cost: $289,601

Institution

• Name: Columbia University (N.Y.)
• Department: Anesthesiology
• Type: Schools of Medicine
• DUNS #: 621889815
• City: New York
• State: NY
• Country: United States
• Zip Code: 10032

Publications

Zhao, Yejun; Sun, Lena (2008) Antidepressants modulate the in vitro inhibitory effects of propofol and ketamine on norepinephrine and serotonin transporter function. J Clin Neurosci 15:1264-9

Zhao, Yejun; Sun, Lena (2004) Perinatal cocaine exposure reduces myocardial norepinephrine transporter function in the neonatal rat. Neurotoxicol Teratol 26:443-50

Sun, Lena S; Quamina, Aaron (2004) Extracellular receptor kinase and cAMP response element binding protein activation in the neonatal rat heart after perinatal cocaine exposure. Pediatr Res 56:947-52

Patberg, Kornelis W; Plotnikov, Alexei N; Quamina, Aaron et al. (2003) Cardiac memory is associated with decreased levels of the transcriptional factor CREB modulated by angiotensin II and calcium. Circ Res 93:472-8

Sun, Lena S; Takuma, Shin; Lui, Rui et al. (2003) The effect of maternal cocaine exposure on neonatal rat cardiac function. Anesth Analg 97:878-82

Sun, Lena S; Quamina, Aaron (2003) Perinatal cocaine exposure stimulates the expression and activation of CREB in the neonatal rat heart. Pediatr Res 53:500-6