Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
5R01DA015148-02
Application #
6704701
Study Section
Special Emphasis Panel (ZRG1-BDCN-4 (01))
Program Officer
Pollock, Jonathan D
Project Start
2003-02-15
Project End
2006-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
2
Fiscal Year
2004
Total Cost
$299,000
Indirect Cost
Name
University of Utah
Department
Genetics
Type
Schools of Medicine
DUNS #
009095365
City
Salt Lake City
State
UT
Country
United States
Zip Code
84112
Osborne-Hereford, Amber V; Rogers, Scott W; Gahring, Lorise C (2008) Neuronal nicotinic alpha7 receptors modulate inflammatory cytokine production in the skin following ultraviolet radiation. J Neuroimmunol 193:130-9
Rogers, Scott W; Weis, Janis J; Ma, Ying et al. (2008) Mouse chromosome 11 harbors genetic determinants of hippocampal strain-specific nicotinic receptor expression. Hippocampus 18:750-7
Gahring, Lorise C; Osborne-Hereford, Amber V; Vasquez-Opazo, Gustavo A et al. (2008) Tumor necrosis factor alpha enhances nicotinic receptor up-regulation via a p38MAPK-dependent pathway. J Biol Chem 283:693-9
Gahring, Lorise C; Rogers, Scott W (2005) Neuronal nicotinic acetylcholine receptor expression and function on nonneuronal cells. AAPS J 7:E885-94
Gahring, Lorise C; Persiyanov, Karina; Rogers, Scott W (2005) Mouse strain-specific changes in nicotinic receptor expression with age. Neurobiol Aging 26:973-80
Gahring, Lorise C; Persiyanov, Karina; Days, Emily L et al. (2005) Age-related loss of neuronal nicotinic receptor expression in the aging mouse hippocampus corresponds with cyclooxygenase-2 and PPAR gamma expression and is altered by long-term NS398 administration. J Neurobiol 62:453-68
Gahring, Lorise C; Days, Emily L; Kaasch, Tuesday et al. (2005) Pro-inflammatory cytokines modify neuronal nicotinic acetylcholine receptor assembly. J Neuroimmunol 166:88-101
Gahring, Lorise C; Persiyanov, Karina; Rogers, Scott W (2004) Neuronal and astrocyte expression of nicotinic receptor subunit beta4 in the adult mouse brain. J Comp Neurol 468:322-33
Gahring, Lorise C; Persiyanov, Karina; Dunn, Diane et al. (2004) Mouse strain-specific nicotinic acetylcholine receptor expression by inhibitory interneurons and astrocytes in the dorsal hippocampus. J Comp Neurol 468:334-46
Gahring, Lorise C; Meyer, Erin L; Rogers, Scott W (2003) Nicotine-induced neuroprotection against N-methyl-D-aspartic acid or beta-amyloid peptide occur through independent mechanisms distinguished by pro-inflammatory cytokines. J Neurochem 87:1125-36