This study proposes to test the efficacy of an ecodevelopmental, parent-centered drug abuse and HIV prevention intervention for Hispanic, behavior problem adolescents and their families (Familias Unidas; United Families). Familias Unidas targets three risk and protective factors for behavior problems, drug abuse and risky sexual behavior: family functioning, parental monitoring, and the adolescents' social cognitive mediators regarding drugs and sex. An indicated sample of 240 behavior problem adolescents attending 8th grade and their primary parent figure will be assessed at Baseline, and at 6-, 18-, and 30- months. Participants will be randomized after baseline into one of two conditions, Familias Unidas or Community Control. Familias Unidas has previously been tested to examine the impact on risk and protective factors for adolescent drug use and HIV in selected samples of Hispanic immigrant adolescents and their families. In the first of two studies, Familias Unidas was shown to be efficacious relative to a no-intervention control condition in increasing parental investment and in reducing adolescent behavior problems. In the second study, Familias Unidas showed promise relative to two attention control conditions in reducing behavior problems and preventing drug use and risky sexual behavior among behavior problem adolescents. Hierarchical Linear Modeling (HLM) will be used to test (H1) the efficacy of Familias Unidas in reducing adolescent behavior problems over time; (H2) the efficacy of Familias Unidas in preventing adolescent drug use over time; and (H3) the efficacy of Familias Unidas in preventing adolescent risky sexual behaviors over time. Additionally HLM will be used to determine whether (H1a) the effect of Familias Unidas on adolescent behavior problems will be mediated by family functioning; (H2a) the effect of Familias Unidas on drug use will be partially mediated by: a) adolescent behavior problems, b) parental monitoring of peers, c) peer behavior problems defined as peer drug use, and d) adolescent social cognitive mediators regarding drugs; and (H3a) the effect of Familias Unidas on risky sexual behavior will be partially mediated by: a) adolescent drug use, b) parental monitoring of peers, c) peer behavior problems defined as peer sexual behavior, and d) adolescent social cognitive mediators regarding sex.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
5R01DA017462-05
Application #
7277207
Study Section
Special Emphasis Panel (ZDA1-KXN-G (29))
Program Officer
Crump, Aria
Project Start
2003-09-30
Project End
2009-08-31
Budget Start
2007-09-01
Budget End
2009-08-31
Support Year
5
Fiscal Year
2007
Total Cost
$502,013
Indirect Cost
Name
University of Miami School of Medicine
Department
Psychiatry
Type
Schools of Medicine
DUNS #
052780918
City
Coral Gables
State
FL
Country
United States
Zip Code
33146
Brincks, Ahnalee; Montag, Samantha; Howe, George W et al. (2018) Addressing Methodologic Challenges and Minimizing Threats to Validity in Synthesizing Findings from Individual-Level Data Across Longitudinal Randomized Trials. Prev Sci 19:60-73
Siddique, Juned; de Chavez, Peter J; Howe, George et al. (2018) Limitations in Using Multiple Imputation to Harmonize Individual Participant Data for Meta-Analysis. Prev Sci 19:95-108
Brincks, Ahnalee; Perrino, Tatiana; Howe, George et al. (2018) Preventing Youth Internalizing Symptoms Through the Familias Unidas Intervention: Examining Variation in Response. Prev Sci 19:49-59
Brown, C Hendricks; Brincks, Ahnalee; Huang, Shi et al. (2018) Two-Year Impact of Prevention Programs on Adolescent Depression: an Integrative Data Analysis Approach. Prev Sci 19:74-94
Perrino, Tatiana; Brincks, Ahnalee; Howe, George et al. (2016) Reducing Internalizing Symptoms Among High-Risk, Hispanic Adolescents: Mediators of a Preventive Family Intervention. Prev Sci 17:595-605
McCollister, Kathryn E; Freitas, Derek M; Prado, Guillermo et al. (2014) Opportunity costs and financial incentives for Hispanic youth participating in a family-based HIV and substance use preventive intervention. J Prim Prev 35:13-20
Perrino, Tatiana; Pantin, Hilda; Prado, Guillermo et al. (2014) Preventing internalizing symptoms among Hispanic adolescents: a synthesis across Familias Unidas trials. Prev Sci 15:917-28
Malcolm, Shandey; Huang, Shi; Cordova, David et al. (2013) Predicting condom use attitudes, norms, and control beliefs in Hispanic problem behavior youth: the effects of family functioning and parent-adolescent communication about sex on condom use. Health Educ Behav 40:384-91
Prado, Guillermo; Huang, Shi; Cordova, David et al. (2013) Ecodevelopmental and intrapersonal moderators of a family based preventive intervention for Hispanic youth: a latent profile analysis. Prev Sci 14:290-9
Cordova, David; Huang, Shi; Pantin, Hilda et al. (2012) Do the effects of a family intervention on alcohol and drug use vary by nativity status? Psychol Addict Behav 26:655-60

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