This application is in response to the following notice: NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications (NOT-OD-09-058). There is considerable evidence that treatment for drug use disorders can lead to substantial improvements in substance use and psychosocial problem severity. However, a significant percentage of patients drop out relatively quickly, rates of relapse are high, and continuing care is often inadequate or unavailable. In our NIDA parent grant, we are testing two extended continuing care models designed to manage patients for up to two years. These models combine low-level telephone-based monitoring and counseling, with an adaptive component to step up level of care when needed. One of these models also includes small incentives for completed continuing care contacts. Data from the first 250 participants indicates these incentives produce very high rates of continuing care contact, compared to the same intervention without incentives (74% vs. 52% of all possible continuing care contacts completed). Preliminary analyses of cocaine urine toxicology samples at 3, 6, 9, and 12 months indicated that both extended care interventions are producing better outcomes than outpatient treatment as usual. In the parent study, we are recruiting insured patients out of publicly funded community programs. The extended continuing care interventions are provided by a group of highly trained and closely supervised counselors. For the supplement, we propose to extend this continuing care model into a new population of high risk individuals, inner city residents without any kind of insurance who seek treatment for cocaine dependence through a special program run by the City of Philadelphia's Behavioral Health Department. We will train city telephone care managers to deliver our telephone continuing care intervention to patients who enter this program, to provide 12 months of regular monitoring, brief counseling, case management and linkage to community supports, and further referral to treatment services as needed. We will randomize 200 participants to receive this intervention or usual care, and follow them up for 12 months. This supplement will provide a more direct test of whether our continuing care model can be implemented successfully by """"""""real world"""""""" publicly funded programs and their staff of paraprofessionals and counselors, and will facilitate the City's transformation into a recovery-oriented, continuing care model of addiction treatment. The University of Pennsylvania School of Medicine contributes substantially to the local economy. In 2008, the School created 37,000 jobs and $5.4 billion in regional economic activity, with the area's highly trained workforce producing more than 24,600 applications for just 840 open Penn staff research positions. The current proposal will create or retain 16 jobs.

Public Health Relevance

Treatment for substance use disorders generally consists of relatively brief episodes of care that do not properly address the chronic, relapsing nature of these disorders. In the parent grant and other prior work, we have developed a telephone-based continuing care model that provides extended care and has proved efficacious in several carefully controlled studies. The proposed supplement will determine whether a 12 month version of this continuing care protocol can be used effectively in disadvantaged cocaine dependent individuals seeking treatment in publicly funded, inner-city programs.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
3R01DA020623-04S1
Application #
7815158
Study Section
Special Emphasis Panel (ZDA1-KXH-C (09))
Program Officer
Mcnamara-Spitznas, Cecilia M
Project Start
2009-09-30
Project End
2013-05-31
Budget Start
2009-09-30
Budget End
2013-05-31
Support Year
4
Fiscal Year
2009
Total Cost
$1,059,107
Indirect Cost
Name
University of Pennsylvania
Department
Psychiatry
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Wimberly, Alexandra S; Hyatt, Jordan M; McKay, James R (2018) Effect of continuing care for people with cocaine dependence on criminal justice sentences. Behav Sci Law 36:116-129
Wimberly, Alexandra S; Stern, Max R; Rosenbach, Sarah B et al. (2017) Challenges to Practicing HIV Sex-Risk Prevention Among People in Continuing Care for Cocaine Addiction. Subst Use Misuse 52:614-623
Wimberly, Alexandra S; Ivey, Megan; Rennert, Lior et al. (2017) Effect of Continuing Care for Cocaine Dependence on HIV Sex-Risk Behaviors. AIDS Behav 21:1082-1090
McCollister, Kathryn; Yang, Xuan; McKay, James R (2016) Cost-effectiveness analysis of a continuing care intervention for cocaine-dependent adults. Drug Alcohol Depend 158:38-44
McKay, James R; Van Horn, Deborah H A; Lynch, Kevin G et al. (2014) Who benefits from extended continuing care for cocaine dependence? Addict Behav 39:660-8
McKay, James R; Van Horn, Deborah H A; Lynch, Kevin G et al. (2013) An adaptive approach for identifying cocaine dependent patients who benefit from extended continuing care. J Consult Clin Psychol 81:1063-73
McKay, James R; Van Horn, Deborah; Rennert, Lior et al. (2013) Factors in sustained recovery from cocaine dependence. J Subst Abuse Treat 45:163-72
Van Horn, Deborah H A; Drapkin, Michelle; Ivey, Megan et al. (2011) Voucher incentives increase treatment participation in telephone-based continuing care for cocaine dependence. Drug Alcohol Depend 114:225-8
McKay, James R (2009) Continuing care research: what we have learned and where we are going. J Subst Abuse Treat 36:131-45
McKay, James R; Carise, Deni (2009) State of the science: Extending the benefits of addiction treatment. J Subst Abuse Treat 36:172-3

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