Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
3R01DA021537-03S1
Application #
7437563
Study Section
NeuroAIDS and other End-Organ Diseases Study Section (NAED)
Program Officer
Khalsa, Jagjitsingh H
Project Start
2006-04-01
Project End
2011-08-31
Budget Start
2007-09-01
Budget End
2008-08-31
Support Year
3
Fiscal Year
2007
Total Cost
$77,203
Indirect Cost
Name
Florida International University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
071298814
City
Miami
State
FL
Country
United States
Zip Code
33199
Kurapati, Kesava Rao V; Atluri, Venkata S; Samikkannu, Thangavel et al. (2015) Natural Products as Anti-HIV Agents and Role in HIV-Associated Neurocognitive Disorders (HAND): A Brief Overview. Front Microbiol 6:1444
Yndart, Adriana; Kaushik, Ajeet; Agudelo, Marisela et al. (2015) Investigation of Neuropathogenesis in HIV-1 Clade B and C Infection Associated with IL-33 and ST2 Regulation. ACS Chem Neurosci 6:1600-12
Atluri, Venkata Subba Rao; Pilakka-Kanthikeel, Sudheesh; Samikkannu, Thangavel et al. (2014) Vorinostat positively regulates synaptic plasticity genes expression and spine density in HIV infected neurons: role of nicotine in progression of HIV-associated neurocognitive disorder. Mol Brain 7:37
Kurapati, Kesava Rao Venkata; Samikkannu, Thangavel; Atluri, Venkata Subba Rao et al. (2014) ?-Amyloid1-42, HIV-1Ba-L (clade B) infection and drugs of abuse induced degeneration in human neuronal cells and protective effects of ashwagandha (Withania somnifera) and its constituent Withanolide A. PLoS One 9:e112818
Kurapati, Kesava Rao Venkata; Atluri, Venkata Subba Rao; Samikkannu, Thangavel et al. (2013) Ashwagandha (Withania somnifera) reverses ?-amyloid1-42 induced toxicity in human neuronal cells: implications in HIV-associated neurocognitive disorders (HAND). PLoS One 8:e77624
Atluri, Venkata Subba Rao; Kanthikeel, Sudheesh P; Reddy, Pichili V B et al. (2013) Human synaptic plasticity gene expression profile and dendritic spine density changes in HIV-infected human CNS cells: role in HIV-associated neurocognitive disorders (HAND). PLoS One 8:e61399
Nair, Madhavan P N; Samikkannu, Thangavel (2012) Differential regulation of neurotoxin in HIV clades: role of cocaine and methamphetamine. Curr HIV Res 10:429-34
Agudelo, Marisela; Yoo, Changwon; Nair, Madhavan P (2012) Alcohol-induced serotonergic modulation: the role of histone deacetylases. Alcohol 46:635-42
Reddy, Pichili Vijaya Bhaskar; Gandhi, Nimisha; Samikkannu, Thangavel et al. (2012) HIV-1 gp120 induces antioxidant response element-mediated expression in primary astrocytes: role in HIV associated neurocognitive disorder. Neurochem Int 61:807-14
Kurapati, Kesava Rao V; Samikkannu, Thangavel; Kadiyala, Dakshayani B et al. (2012) Combinatorial cytotoxic effects of Curcuma longa and Zingiber officinale on the PC-3M prostate cancer cell line. J Basic Clin Physiol Pharmacol 23:139-46

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