During the current grant period the physiologic framework underlying typical speech development has been quantified for the major speech systems (i.e., respiratory, phonatory, and articulatory systems) in children from 3-months to 4-years of age. This proposed continuation integrates these system-specific findings across systems in typically developing children and extends these studies to developmental speech impairment. Well-developed descriptive techniques in speech physiology, phonology, speech and language development, and computational modeling of complex systems provide convergent methods for studying speech development and speech impairment. Neural network-based computational modeling will be used to relate events across speech systems and across levels of observation (i.e., physiologic observations and speech output) and to map the transform of physiologic events to speech output (i.e., phonetic and prosodic). Three hundred 36-48-month-old children, 240 of whom will exhibit speech delay of unknown origin, will be studied using detailed phonetic description, physiologic description (including respiratory, phonatory, and articulatory signals). Connectionist models will identify clustering of covarying physiologic parameters, speech production parameters, and linkages of clusters across these two domains. These analyses will yield a map of the physiologic correlates of speech impairment, and will provide a basis for evaluating current nosologies of child speech delay of unknown origin.

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Research Project (R01)
Project #
5R01DC000822-11
Application #
6516096
Study Section
Special Emphasis Panel (ZRG1-BBBP-4 (02))
Program Officer
Shekim, Lana O
Project Start
1991-05-01
Project End
2006-05-31
Budget Start
2002-06-01
Budget End
2003-05-31
Support Year
11
Fiscal Year
2002
Total Cost
$491,694
Indirect Cost
Name
University of Washington
Department
Other Health Professions
Type
Schools of Arts and Sciences
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
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Connaghan, Kathryn P; Moore, Christopher A (2013) Indirect estimates of jaw muscle tension in children with suspected hypertonia, children with suspected hypotonia, and matched controls. J Speech Lang Hear Res 56:123-36
Vick, Jennell C; Campbell, Thomas F; Shriberg, Lawrence D et al. (2012) Distinct developmental profiles in typical speech acquisition. J Neurophysiol 107:2885-900
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Che, Wei-Chun; Wang, Yu-Tsai; Lu, Hsiu-Jung et al. (2011) Respiratory changes during reading in Mandarin-speaking adolescents with prelingual hearing impairment. Folia Phoniatr Logop 63:275-80
Wang, Yu-Tsai; Green, Jordan R; Nip, Ignatius S B et al. (2010) Breath group analysis for reading and spontaneous speech in healthy adults. Folia Phoniatr Logop 62:297-302
Steeve, Roger W; Price, Christiana M (2010) Investigating the use of coherence analysis on mandibular electromyograms to investigate neural control of early oromandibular behaviours: A pilot study. Clin Linguist Phon 24:485-501
Steeve, Roger W (2010) Babbling and Chewing: Jaw Kinematics from 8 to 22 months. J Phon 38:445-458
Reilly, Kevin J; Moore, Christopher A (2009) Respiratory movement patterns during vocalizations at 7 and 11 months of age. J Speech Lang Hear Res 52:223-39

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