The purpose of this proposal is to longitudinally compare outcomes of surgical treatments for paralytic dysphonia. Vocal performance of patients who suffer from unilateral vocal fold paralysis will be assessed before and after surgical correction of the glottal gap by procedures which either: a) augment, b) medialize, or c) reinnervate the paralyzed vocal fold. Characteristics of vocal performance will be longitudinally assessed: a) acoustically, b) aerodynamically, and c) kinematically. Parameters of acoustic performance are to include measures of fundamental frequency, intensity, pitch range, periodicity/noise. Rate of glottal air flow will be measured as well as vibratory characteristics of the vocal folds by videostroboscopy. A comparison of treatment efficacy is intended to identify or clarify existing a) indications, b) contraindications, c) timing of surgical intervention, and d) long term effects. The results of this study will provide a basis for much needed refinement of medical and surgical strategies in the treatment of glottal incompetence due to paralysis.

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Research Project (R01)
Project #
5R01DC001147-02
Application #
3217889
Study Section
Special Emphasis Panel (SRC (03))
Project Start
1990-09-28
Project End
1993-08-31
Budget Start
1991-09-01
Budget End
1992-08-31
Support Year
2
Fiscal Year
1991
Total Cost
Indirect Cost
Name
Yale University
Department
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
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Leder, S B; Sasaki, C T (1994) Long-term changes in vocal quality following Isshiki thyroplasty type I. Laryngoscope 104:275-7
Till, J A; Crumley, R L; Jafari, M et al. (1994) Aerodynamic and temporal disruptions of speech in laryngeal insufficiency. Arch Otolaryngol Head Neck Surg 120:317-25
Horowitz, J B; Sasaki, C T (1993) Effect of cricopharyngeus myotomy on postlaryngectomy pharyngeal contraction pressures. Laryngoscope 103:138-40