Neurogenic Regulation of Cochlear Blood Flow

Wangemann, A. Philine

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute on Deafness and Other Communication Disorders (NIDCD)
• Type: Research Project (R01)
• Project #: 1R01DC004280-01
• Application #: 6028183
• Study Section: Special Emphasis Panel (ZRG1-IFCN-6 (01))
• Project Start: 1999-04-01
• Project End: 2004-03-31
• Budget Start: 1999-04-01
• Budget End: 2000-03-31
• Support Year: 1
• Fiscal Year: 1999

Institution

• Name: Kansas State University
• Department: Anatomy/Cell Biology
• Type: Schools of Veterinary Medicine
• City: Manhattan
• State: KS
• Country: United States
• Zip Code: 66506

Publications

Krishnamoorthy, Gayathri; Reimann, Katrin; Wangemann, Philine (2016) Ryanodine-induced vasoconstriction of the gerbil spiral modiolar artery depends on the Ca(2+) sensitivity but not on Ca(2+) sparks or BK channels. BMC Physiol 16:6

Reimann, Katrin; Krishnamoorthy, Gayathri; Wangemann, Philine (2013) NOS inhibition enhances myogenic tone by increasing rho-kinase mediated Ca2+ sensitivity in the male but not the female gerbil spiral modiolar artery. PLoS One 8:e53655

Witt, Kelly M; Bockman, Charles S; Dang, Herbert K et al. (2012) Molecular and pharmacological characteristics of the gerbil ?(1a)-adrenergic receptor. Hear Res 283:144-50

Reimann, Katrin; Krishnamoorthy, Gayathri; Wier, Withrow Gil et al. (2011) Gender differences in myogenic regulation along the vascular tree of the gerbil cochlea. PLoS One 6:e25659

Krishnamoorthy, Gayathri; Regehr, Keil; Berge, Samantha et al. (2011) Calcium sparks in the intact gerbil spiral modiolar artery. BMC Physiol 11:15

Scherer, Elias Q; Yang, Jingli; Canis, Martin et al. (2010) Tumor necrosis factor-ýý enhances microvascular tone and reduces blood flow in the cochlea via enhanced sphingosine-1-phosphate signaling. Stroke 41:2618-24

Wangemann, Philine; Wonneberger, Kai (2005) Neurogenic regulation of cochlear blood flow occurs along the basilar artery, the anterior inferior cerebellar artery and at branch points of the spiral modiolar artery. Hear Res 209:91-6

Herzog, M; Scherer, E Q; Albrecht, B et al. (2002) CGRP receptors in the gerbil spiral modiolar artery mediate a sustained vasodilation via a transient cAMP-mediated Ca2+-decrease. J Membr Biol 189:225-36

Scherer, Elias Q; Herzog, Michael; Wangemann, Philine (2002) Endothelin-1-induced vasospasms of spiral modiolar artery are mediated by rho-kinase-induced Ca(2+) sensitization of contractile apparatus and reversed by calcitonin gene-related Peptide. Stroke 33:2965-71

Wangemann, Philine (2002) Cochlear blood flow regulation. Adv Otorhinolaryngol 59:51-7