Abstract

This application represents a three-year competing revision supplement to research grant R01 DC010494. The central focus of the parent grant was to investigate the potential of optimization of fitting parameters in cochlear implants. This was proposed with the use of a portable research speech processor that allows users to: (a) change MAP parameters based on two outcome measures, namely quality and intelligibility (b) customize the MAP to different listening situations for maximum benefit, and (c) collect feedback and recordings of real acoustic signals for further analysis. Unilateral, bilateral and bimodal users will participate in double-blind field trials to assess the true benefit of a portable speech processor that can be easily customized by the users to optimize their listening experience. For portable cochlear implant speech processor, the PDA platform, which was developed in our lab under an NIDCD contract, will be used. The PDA processor was recently approved by FDA for IDE clinical trials and distributed to 8 research labs and clinics. Given that the PDA processor is currently in IDE clinical trials, clinical monitoring has to be set in place and ongoing with the research studies proposed in the parent R01. Support for the cost of clinical monitoring is requested with the current competing revision application. Support for one full-time engineer who will be responsible for maintaining all IDE-related documentation from the participant clinics and for providing technical support for all software running on the PDA processor is also requested. This supplemental funding will enable the PI to pursue the goals of the original parent R01 application and remain compliant with FDA regulations.

Public Health Relevance

The outcomes of this work can greatly benefit the overall quality of life for a large number of cochlear implant users. Cochlear implant users who are able to communicate effectively in noisy environments have greater opportunity for integration into mainstream education, increase their productivity at home or work and contribute more in the nation's economic growth and competitiveness.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Research Project (R01)
Project #
3R01DC010494-02S1
Application #
8385352
Study Section
Auditory System Study Section (AUD)
Program Officer
Miller, Roger
Project Start
2010-01-01
Project End
2015-06-30
Budget Start
2012-07-01
Budget End
2013-06-30
Support Year
2
Fiscal Year
2012
Total Cost
$191,250
Indirect Cost
$66,250

  Institution

Name
University of Texas-Dallas
Department
Engineering (All Types)
Type
Schools of Engineering
DUNS #
800188161
City
Richardson
State
TX
Country
United States
Zip Code
75080

  Publications

Saba, Juliana N; Ali, Hussnain; Hansen, John H L (2018) Formant priority channel selection for an ""n-of-m"" sound processing strategy for cochlear implants. J Acoust Soc Am 144:3371
Dorman, Michael F; Natale, Sarah Cook; Butts, Austin M et al. (2017) The Sound Quality of Cochlear Implants: Studies With Single-sided Deaf Patients. Otol Neurotol 38:e268-e273
Lee, Jaewook; Ali, Hussnain; Ziaei, Ali et al. (2017) The Lombard effect observed in speech produced by cochlear implant users in noisy environments: A naturalistic study. J Acoust Soc Am 141:2788
Lövgren, Tanja; Sarhan, Dhifaf; Truxová, Iva et al. (2017) Enhanced stimulation of human tumor-specific T cells by dendritic cells matured in the presence of interferon-? and multiple toll-like receptor agonists. Cancer Immunol Immunother 66:1333-1344
Dorman, Michael F; Liss, Julie; Wang, Shuai et al. (2016) Experiments on Auditory-Visual Perception of Sentences by Users of Unilateral, Bimodal, and Bilateral Cochlear Implants. J Speech Lang Hear Res 59:1505-1519
Jones, Heath G; Kan, Alan; Litovsky, Ruth Y (2016) The Effect of Microphone Placement on Interaural Level Differences and Sound Localization Across the Horizontal Plane in Bilateral Cochlear Implant Users. Ear Hear 37:e341-5
Dorman, Michael F; Loiselle, Louise H; Cook, Sarah J et al. (2016) Sound Source Localization by Normal-Hearing Listeners, Hearing-Impaired Listeners and Cochlear Implant Listeners. Audiol Neurootol 21:127-31
Hossain, Shaikat; Montazeri, Vahid; Assmann, Peter F et al. (2015) Precedence based speech segregation in bilateral cochlear implant users. J Acoust Soc Am 138:EL545-50
Kan, Alan; Litovsky, Ruth Y (2015) Binaural hearing with electrical stimulation. Hear Res 322:127-37
Falk, Tiago H; Parsa, Vijay; Santos, João F et al. (2015) Objective Quality and Intelligibility Prediction for Users of Assistive Listening Devices. IEEE Signal Process Mag 32:114-124

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