Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Research Project (R01)
Project #
5R01DE003738-23
Application #
2128921
Study Section
Allergy and Immunology Study Section (ALY)
Project Start
1976-06-01
Project End
1997-02-28
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
23
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Duke University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
071723621
City
Durham
State
NC
Country
United States
Zip Code
27705
Richardson, Ricardo M; Tokunaga, Kenzo; Marjoram, Robin et al. (2003) Interleukin-8-mediated heterologous receptor internalization provides resistance to HIV-1 infectivity. Role of signal strength and receptor desensitization. J Biol Chem 278:15867-73
Richardson, Ricardo M; Marjoram, Robin J; Barak, Larry S et al. (2003) Role of the cytoplasmic tails of CXCR1 and CXCR2 in mediating leukocyte migration, activation, and regulation. J Immunol 170:2904-11
Barr, Alastair J; Marjoram, Robin; Xu, Jing et al. (2002) Phospholipase C-beta 2 interacts with mitogen-activated protein kinase kinase 3. Biochem Biophys Res Commun 293:647-52
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Barr, A J; Ali, H; Haribabu, B et al. (2000) Identification of a region at the N-terminus of phospholipase C-beta 3 that interacts with G protein beta gamma subunits. Biochemistry 39:1800-6
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Haribabu, B; Verghese, M W; Steeber, D A et al. (2000) Targeted disruption of the leukotriene B(4) receptor in mice reveals its role in inflammation and platelet-activating factor-induced anaphylaxis. J Exp Med 192:433-8
Haribabu, B; Zhelev, D V; Pridgen, B C et al. (1999) Chemoattractant receptors activate distinct pathways for chemotaxis and secretion. Role of G-protein usage. J Biol Chem 274:37087-92
Ali, H; Sozzani, S; Fisher, I et al. (1998) Differential regulation of formyl peptide and platelet-activating factor receptors. Role of phospholipase Cbeta3 phosphorylation by protein kinase A. J Biol Chem 273:11012-6
Richardson, R M; Ali, H; Pridgen, B C et al. (1998) Multiple signaling pathways of human interleukin-8 receptor A. Independent regulation by phosphorylation. J Biol Chem 273:10690-5

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