Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Research Project (R01)
Project #
5R01DE004529-18
Application #
2128974
Study Section
Oral Biology and Medicine Subcommittee 1 (OBM)
Project Start
1976-06-01
Project End
1997-04-30
Budget Start
1995-05-01
Budget End
1997-04-30
Support Year
18
Fiscal Year
1995
Total Cost
Indirect Cost

  Institution

Name
University of Florida
Department
Dentistry
Type
Schools of Dentistry
DUNS #
073130411
City
Gainesville
State
FL
Country
United States
Zip Code
32611

  Publications

Hillman, J D; McDonell, E; Cramm, T et al. (2009) A spontaneous lactate dehydrogenase deficient mutant of Streptococcus rattus for use as a probiotic in the prevention of dental caries. J Appl Microbiol 107:1551-8
Smith, Leif; Zachariah, Cherian; Thirumoorthy, Ramanan et al. (2003) Structure and dynamics of the lantibiotic mutacin 1140. Biochemistry 42:10372-84
Wu, Yi; Lee, Seok-Woo; Hillman, Jeffrey D et al. (2002) Identification and testing of Porphyromonas gingivalis virulence genes with a pPGIVET system. Infect Immun 70:928-37
Hillman, J D; Brooks, T A; Michalek, S M et al. (2000) Construction and characterization of an effector strain of Streptococcus mutans for replacement therapy of dental caries. Infect Immun 68:543-9
Smith, L; Novak, J; Rocca, J et al. (2000) Covalent structure of mutacin 1140 and a novel method for the rapid identification of lantibiotics. Eur J Biochem 267:6810-6
Cvitkovitch, D G; Gutierrez, J A; Behari, J et al. (2000) Tn917-lac mutagenesis of Streptococcus mutans to identify environmentally regulated genes. FEMS Microbiol Lett 182:149-54
Gutierrez, J A; Crowley, P J; Cvitkovitch, D G et al. (1999) Streptococcus mutans ffh, a gene encoding a homologue of the 54 kDa subunit of the signal recognition particle, is involved in resistance to acid stress. Microbiology 145 ( Pt 2):357-66
Hillman, J D; Novak, J; Sagura, E et al. (1998) Genetic and biochemical analysis of mutacin 1140, a lantibiotic from Streptococcus mutans. Infect Immun 66:2743-9
Crowley, P J; Gutierrez, J A; Hillman, J D et al. (1997) Genetic and physiologic analysis of a formyl-tetrahydrofolate synthetase mutant of Streptococcus mutans. J Bacteriol 179:1563-72
Gutierrez, J A; Crowley, P J; Brown, D P et al. (1996) Insertional mutagenesis and recovery of interrupted genes of Streptococcus mutans by using transposon Tn917: preliminary characterization of mutants displaying acid sensitivity and nutritional requirements. J Bacteriol 178:4166-75

Showing the most recent 10 out of 22 publications