The immediate specific aim of this study is to determine the diagnostic accuracy of interpretation of subtraction images which is obtainable by use of state-of-the-art image analysis systems. It is proposed to achieve the stated specific aim by comparing the observer performance for the interpretation of subtraction images using the different image analysis systems. Focus will be directed to three areas of study: 1. technics for standardizing x-ray beam angulation 2. comparison of electronic with film-based methods for image acquisition. 3. after the fact minimization of projection angle discrepancies of subtraction images generated from radiographs differing in projection geometry. 1.Technics for standardizing x-ray beam angulation: Three methods for obtaining radiographs believed to be suitable for subtraction radiography will be investigated for their contribution of diagnostic accuracy: a. a rigidly fixed stent based system, b. an uncoupled stent based system, c. a non-stent based system using extra-oral fixation. Angle discrepancy of the x-ray tube and subject at a 6 months time interval will be determined by deflection of a light beam from a mirror reproducibly positioned on the patient. The mirror will be so positioned by means of a device fitting on to 2 adjacent bracketed teeth. 2. Comparison of electronic with film-based methods for image acquisition: An ancillary, but nevertheless very important component of this study is to compare the diagnostic accuracy for a film-based system using rectangular collimation to an electronic sensor (Trophy) system. An overriding goal is to obtain images with minimum radiation exposure to the patient. 3.Improvement of diagnostic accuracy due to misangulation error: We will attempt to test these three types of systems at their optimal potential. However, since no system is anticipated to function perfectly we propose to develop algorithmic methodologies to ameliorate slight misangulation errors and test whether these will enhance accuracy of interpretation of subtraction images.

Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Research Project (R01)
Project #
5R01DE008544-06
Application #
3222316
Study Section
Oral Biology and Medicine Subcommittee 1 (OBM)
Project Start
1988-05-01
Project End
1995-04-30
Budget Start
1993-05-01
Budget End
1994-04-30
Support Year
6
Fiscal Year
1993
Total Cost
Indirect Cost
Name
State University of New York at Buffalo
Department
Type
Schools of Dentistry
DUNS #
038633251
City
Buffalo
State
NY
Country
United States
Zip Code
14260
Hausmann, E; Allen, K (1997) Reproducibility of bone height measurements made on serial radiographs. J Periodontol 68:839-41
Hausmann, E; Kutlubay, M E; Odrobina, D et al. (1995) Studies on the angular reproducibility of positioning patients adjacent to an x-ray tube. 2. A new electronically guided, force-sensitive sensor-based alignment system. J Periodontal Res 30:294-7
Allen, K M; Hausmann, E (1995) Model fit and measurement outcome in attachment measurements: a simulation study. J Periodontal Res 30:15-22
Samarabandu, J; Allen, K M; Hausmann, E et al. (1994) Algorithm for the automated alignment of radiographs for image subtraction. Oral Surg Oral Med Oral Pathol 77:75-9
Katsarsky, J W; Levine, M S; Allen, K M et al. (1994) Detection of experimentally induced lesions in subtraction images of cancellous alveolar bone. Oral Surg Oral Med Oral Pathol 77:674-7
Carpio, L C; Hausmann, E; Dunford, R G et al. (1994) Evaluation of a simple modified radiographic alignment system for routine use. J Periodontol 65:62-7
Hausmann, E; Allen, K; Norderyd, J et al. (1994) Studies on the relationship between changes in radiographic bone height and probing attachment. J Clin Periodontol 21:128-32
Allen, K M; Hausmann, E; Kutlubay, M E et al. (1994) Studies of the angular reproducibility of positioning patients adjacent to an x-ray tube: 1. Stent-rod based and extra-oral systems. J Periodontal Res 29:174-8
Davis, M; Allen, K M; Hausmann, E (1994) Effects of small angle discrepancies on interpretations of subtraction images. Oral Surg Oral Med Oral Pathol 78:397-400
Allen, K; Emrich, L; Piedmonte, M et al. (1992) Relationship of texture measurements to the prediction of correct evaluations in subtraction radiography. J Periodontal Res 27:197-206

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