The overall aim of this study is to conduct a rigorous investigation into the relative advantages and disadvantages of the use of extraction strategies versus non-extraction strategies in the orthodontic treatment of adult patients with mild to moderately severe Angle Class I and Class II malocclusions. For the purposes of this study, adult patients are defined as individuals who commence active orthodontic treatment after their twentieth birthday. The study will have both a retrospective component and a prospective component and will constitute an interinstitutional collaboration between the Department of Growth and Development of the University of California, San Francisco and the Department of Orthodontics of the University of the Pacific. During the initial five year grant period, we will seek the characterize and compare the effects of adult extraction and non- extraction strategies in two main areas: 1. Morphologic changes associated with treatment, including (a) Changes during treatment in face form, arch form, tooth alignment and tooth intercuspation, and (b) Post-treatment stability of the changes noted in (a), and 2. Physiological costs and benefits of treatment, particularly in terms of periodontal pathology. We will commence and complete the retrospective component of the study and the active phase of treatment for the first cohort of subjects in the prospective component. The retrospective component will examine a representative group of subjects treated earlier by expert orthodontists. The prospective component will include a randomized clinical trial of new design with provision for clinician-preferred treatment.

Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Research Project (R01)
Project #
5R01DE008713-04
Application #
3222577
Study Section
Special Emphasis Panel (SRC)
Project Start
1988-08-01
Project End
1993-07-31
Budget Start
1991-08-01
Budget End
1992-07-31
Support Year
4
Fiscal Year
1991
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Type
Schools of Dentistry
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Oh, Hee Soo; Korn, Edward L; Zhang, Xiaoyun et al. (2009) Correlations between cephalometric and photographic measurements of facial attractiveness in Chinese and US patients after orthodontic treatment. Am J Orthod Dentofacial Orthop 136:762.e1-14; discussion 762-3
Liu, Yan; Korn, Edward L; Oh, Hee Soo et al. (2009) Comparison of Chinese and US orthodontists' averaged evaluations of ""facial attractiveness"" from end-of-treatment facial photographs. Am J Orthod Dentofacial Orthop 135:621-34
Xu, Tian-Min; Korn, Edward L; Liu, Yan et al. (2008) .Facial attractiveness: ranking of end-of-treatment facial photographs by pairs of Chinese and US orthodontists. Am J Orthod Dentofacial Orthop 134:74-84
Xu, T; Baumrind, S (2001) [Inferring landmark displacements from changes in cephalometric angles] Zhonghua Kou Qiang Yi Xue Za Zhi 36:269-72
Xu, T; Ahn, J; Baumrind, S (2000) [Sensitivity of four representative angular cephalometric measures] Zhonghua Kou Qiang Yi Xue Za Zhi 35:221-3
Baumrind, S (1998) Unbiased quantitative testing of conventional orthodontic beliefs. Semin Orthod 4:3-16
Baumrind, S (1998) Clinical studies in orthodontics--an overview of NIDR-sponsored clinical orthodontic studies in the US. Clin Orthod Res 1:80-7
Baumrind, S (1998) Adult orthodontic therapy: extraction versus non-extraction. Clin Orthod Res 1:130-41
Baumrind, S; Bravo, L A; Ben-Bassat, Y et al. (1997) Lower molar and incisor displacement associated with mandibular remodeling. Angle Orthod 67:93-102
Baumrind, S; Korn, E L; Boyd, R L (1996) Apical root resorption in orthodontically treated adults. Am J Orthod Dentofacial Orthop 110:311-20

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