Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Research Project (R01)
Project #
5R01DE009540-06
Application #
2130606
Study Section
Oral Biology and Medicine Subcommittee 1 (OBM)
Project Start
1991-04-01
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Thomas Jefferson University
Department
Pathology
Type
Schools of Medicine
DUNS #
061197161
City
Philadelphia
State
PA
Country
United States
Zip Code
19107
Nugent, P; Greene, R M (1998) Use of antisense oligonucleotides to study the role of CRABPs in retinoic acid-induced gene expression. Methods Mol Biol 89:191-202
Weston, W M; Potchinsky, M B; Lafferty, C M et al. (1998) Cross-talk between signaling pathways in murine embryonic palate cells: effect of TGF beta and cAMP on EGF-induced DNA synthesis. In Vitro Cell Dev Biol Anim 34:74-8
Potchinsky, M B; Lloyd, M R; Weston, W M et al. (1998) Selective modulation of MAP kinase in embryonic palate cells. J Cell Physiol 176:266-80
Potchinsky, M B; Weston, W M; Lloyd, M R et al. (1997) TGF-beta signaling in murine embryonic palate cells involves phosphorylation of the CREB transcription factor. Exp Cell Res 231:96-103
Potchinsky, M; Nugent, P; Lafferty, C et al. (1996) Effects of dexamethasone on the expression of transforming growth factor-beta in mouse embryonic palatal mesenchymal cells. J Cell Physiol 166:380-6
Nugent, P; Potchinsky, M; Lafferty, C et al. (1995) TGF-beta modulates the expression of retinoic acid-induced RAR-beta in primary cultures of embryonic palate cells. Exp Cell Res 220:495-500
Weston, W M; Nugent, P; Greene, R M (1995) Inhibition of retinoic-acid-induced gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Biochem Biophys Res Commun 207:690-4
Nugent, P; Greene, R M (1995) Antisense oligonucleotides to CRABP I and II alter the expression of TGF-beta 3, RAR-beta, and tenascin in primary cultures of embryonic palate cells. In Vitro Cell Dev Biol Anim 31:553-8
Nugent, P; Greene, R M (1994) Interactions between the transforming growth factor beta (TGF beta) and retinoic acid signal transduction pathways in murine embryonic palatal cells. Differentiation 58:149-55
Gehris, A L; Pisano, M M; Nugent, P et al. (1994) Regulation of TGF beta 3 gene expression in embryonic palatal tissue. In Vitro Cell Dev Biol Anim 30A:671-9

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