Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Research Project (R01)
Project #
5R01DE009677-05
Application #
2130692
Study Section
Oral Biology and Medicine Subcommittee 1 (OBM)
Project Start
1991-02-01
Project End
1997-01-31
Budget Start
1995-02-10
Budget End
1997-01-31
Support Year
5
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Tufts University
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02111
Serruto, Davide; Spadafina, Tiziana; Ciucchi, Laura et al. (2010) Neisseria meningitidis GNA2132, a heparin-binding protein that induces protective immunity in humans. Proc Natl Acad Sci U S A 107:3770-5
Chintalacharuvu, Koteswara R; Chuang, Philip D; Dragoman, Ashley et al. (2003) Cleavage of the human immunoglobulin A1 (IgA1) hinge region by IgA1 proteases requires structures in the Fc region of IgA. Infect Immun 71:2563-70
Hendrixson, D R; Qiu, J; Shewry, S C et al. (2003) Human milk lactoferrin is a serine protease that cleaves Haemophilus surface proteins at arginine-rich sites. Mol Microbiol 47:607-17
Plaut, A G; Qiu, J; St Geme 3rd, J W (2000) Human lactoferrin proteolytic activity: analysis of the cleaved region in the IgA protease of Haemophilus influenzae. Vaccine 19 Suppl 1:S148-52
Smith, D J; King, W F; Gilbert, J V et al. (1998) Structural integrity of infant salivary immunoglobulin A (IgA) in IgA1 protease-rich environments. Oral Microbiol Immunol 13:89-96
Qiu, J; Hendrixson, D R; Baker, E N et al. (1998) Human milk lactoferrin inactivates two putative colonization factors expressed by Haemophilus influenzae. Proc Natl Acad Sci U S A 95:12641-6
Wani, J H; Gilbert, J V; Plaut, A G et al. (1996) Identification, cloning, and sequencing of the immunoglobulin A1 protease gene of Streptococcus pneumoniae. Infect Immun 64:3967-74
Stenberg, L; Qiu, J; Lindahl, G et al. (1996) Lack of interference between IgA-binding proteins and IgA proteases of human pathogenic bacteria. J Med Microbiol 44:65-9
Kane, A V; Plaut, A G (1996) Unique susceptibility of Helicobacter pylori to simethicone emulsifiers in alimentary therapeutic agents. Antimicrob Agents Chemother 40:500-2
Plaut, A G; Wright, A (1995) Immunoglobulin A-metallo-type specific prolyl endopeptidases. Methods Enzymol 248:634-42

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