Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Research Project (R01)
Project #
5R01DE009851-05
Application #
2130895
Study Section
Special Emphasis Panel (ZRG4-OBM-2 (06))
Project Start
1991-08-01
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Ohio State University
Department
Dentistry
Type
Schools of Dentistry
DUNS #
098987217
City
Columbus
State
OH
Country
United States
Zip Code
43210
Stehle, H W; Leblebicioglu, B; Walters, J D (2001) Short-chain carboxylic acids produced by gram-negative anaerobic bacteria can accelerate or delay polymorphonuclear leukocyte apoptosis in vitro. J Periodontol 72:1059-63
Fernandez, M C; Marucha, P T; Rojas, I G et al. (2000) The role of protein kinase C and calcium in induction of human polymorphonuclear leukocyte IL-1 beta gene expression by GM-CSF. Cytokine 12:445-9
Preshaw, P M; Schifferle, R E; Walters, J D (1999) Porphyromonas gingivalis lipopolysaccharide delays human polymorphonuclear leukocyte apoptosis in vitro. J Periodontal Res 34:197-202
Leblebicioglu, B; Walters, J (1999) Alkaline conditions accelerate polymorphonuclear leukocyte apoptosis in vitro. Infect Immun 67:2019-21
Walters, J D; Zhang, F; Nakkula, R J (1999) Mechanisms of fluoroquinolone transport by human neutrophils. Antimicrob Agents Chemother 43:2710-5
Ratasirayakorn, W; Leone, P; Leblebicioglu, B et al. (1999) Polyamines found in the inflamed periodontium inhibit priming and apoptosis in human polymorphonuclear leukocytes. J Periodontol 70:179-84
Walters, J D; Cario, A C; Danne, M M et al. (1998) An inhibitor of ornithine decarboxylase antagonizes superoxide generation by primed human polymorphonuclear leukocytes. J Inflamm 48:40-6
Loo, K C; Cario, A C; Zhang, F et al. (1997) Regulation of ciprofloxacin uptake in human promyelocytic leukemia cells and polymorphonuclear leukocytes. J Leukoc Biol 61:619-23
Leblebicioglu, B; Lim, J S; Cario, A C et al. (1996) pH changes observed in the inflamed gingival crevice modulate human polymorphonuclear leukocyte activation in vitro. J Periodontol 67:472-7
Fernandez, M C; Walters, J; Marucha, P (1996) Transcriptional and post-transcriptional regulation of GM-CSF-induced IL-1 beta gene expression in PMN. J Leukoc Biol 59:598-603

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