Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Research Project (R01)
Project #
1R01DE011117-01A2
Application #
2132234
Study Section
Oral Biology and Medicine Subcommittee 1 (OBM)
Project Start
1996-04-01
Project End
1999-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Biology
Type
Schools of Dentistry
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Sweier, Domenica G; Shelburne, P Sandra; Giannobile, William V et al. (2009) Immunoglobulin G (IgG) class, but Not IgA or IgM, antibodies to peptides of the Porphyromonas gingivalis chaperone HtpG predict health in subjects with periodontitis by a fluorescence enzyme-linked immunosorbent assay. Clin Vaccine Immunol 16:1766-73
Shelburne, Charles E; Shelburne, P Sandra; Dhople, Vishnu M et al. (2008) Serum antibodies to Porphyromonas gingivalis chaperone HtpG predict health in periodontitis susceptible patients. PLoS One 3:e1984
Shelburne, Charles E; Coopamah, Malini D; Sweier, Domenica G et al. (2007) HtpG, the Porphyromonas gingivalis HSP-90 homologue, induces the chemokine CXCL8 in human monocytic and microvascular vein endothelial cells. Cell Microbiol 9:1611-9
Shelburne, Charles E; An, Florence Y; Dholpe, Vishnu et al. (2007) The spectrum of antimicrobial activity of the bacteriocin subtilosin A. J Antimicrob Chemother 59:297-300
Kozarov, Emil; Sweier, Domenica; Shelburne, Charles et al. (2006) Detection of bacterial DNA in atheromatous plaques by quantitative PCR. Microbes Infect 8:687-93
Dhople, Vishnu; Krukemeyer, Amy; Ramamoorthy, Ayyalusamy (2006) The human beta-defensin-3, an antibacterial peptide with multiple biological functions. Biochim Biophys Acta 1758:1499-512
Ramamoorthy, Ayyalusamy; Thennarasu, Sathiah; Tan, Anmin et al. (2006) Deletion of all cysteines in tachyplesin I abolishes hemolytic activity and retains antimicrobial activity and lipopolysaccharide selective binding. Biochemistry 45:6529-40
Shelburne, Charles E; Coulter, Wilson A; Olguin, De'avlin et al. (2005) Induction of {beta}-defensin resistance in the oral anaerobe Porphyromonas gingivalis. Antimicrob Agents Chemother 49:183-7
Kozarov, Emil V; Dorn, Brian R; Shelburne, Charles E et al. (2005) Human atherosclerotic plaque contains viable invasive Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis. Arterioscler Thromb Vasc Biol 25:e17-8
Shelburne, C E; Gleason, R M; Coulter, W A et al. (2005) Differential display analysis of Porphyromonas gingivalis gene activation response to heat and oxidative stress. Oral Microbiol Immunol 20:233-8

Showing the most recent 10 out of 18 publications