Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Research Project (R01)
Project #
5R01DE016715-05
Application #
7759574
Study Section
Oral, Dental and Craniofacial Sciences Study Section (ODCS)
Program Officer
Lunsford, Dwayne
Project Start
2006-02-21
Project End
2013-01-31
Budget Start
2010-02-01
Budget End
2013-01-31
Support Year
5
Fiscal Year
2010
Total Cost
$265,256
Indirect Cost
Name
University of Florida
Department
Dentistry
Type
Schools of Dentistry
DUNS #
969663814
City
Gainesville
State
FL
Country
United States
Zip Code
32611
Alaoui-El-Azher, Mounia; Mans, Jeffrey J; Baker, Henry V et al. (2010) Role of the ATM-checkpoint kinase 2 pathway in CDT-mediated apoptosis of gingival epithelial cells. PLoS One 5:e11714
Mans, Jeffrey J; Hendrickson, Erik L; Hackett, Murray et al. (2010) Cellular and bacterial profiles associated with oral epithelium-microbiota interactions. Periodontol 2000 52:207-17
Mans, Jeffrey J; von Lackum, Kate; Dorsey, Cassandra et al. (2009) The degree of microbiome complexity influences the epithelial response to infection. BMC Genomics 10:380
Papapanou, Panos N; Behle, Jan H; Kebschull, Moritz et al. (2009) Subgingival bacterial colonization profiles correlate with gingival tissue gene expression. BMC Microbiol 9:221
Demmer, Ryan T; Behle, Jan H; Wolf, Dana L et al. (2008) Transcriptomes in healthy and diseased gingival tissues. J Periodontol 79:2112-24
Hasegawa, Yoshiaki; Tribble, Gena D; Baker, Henry V et al. (2008) Role of Porphyromonas gingivalis SerB in gingival epithelial cell cytoskeletal remodeling and cytokine production. Infect Immun 76:2420-7
Handfield, M; Baker, H V; Lamont, R J (2008) Beyond good and evil in the oral cavity: insights into host-microbe relationships derived from transcriptional profiling of gingival cells. J Dent Res 87:203-23
Mao, Song; Park, Yoonsuk; Hasegawa, Yoshiaki et al. (2007) Intrinsic apoptotic pathways of gingival epithelial cells modulated by Porphyromonas gingivalis. Cell Microbiol 9:1997-2007
Hasegawa, Yoshiaki; Mans, Jeffrey J; Mao, Song et al. (2007) Gingival epithelial cell transcriptional responses to commensal and opportunistic oral microbial species. Infect Immun 75:2540-7
Mans, Jeffrey J; Lamont, Richard J; Handfield, Martin (2006) Microarray analysis of human epithelial cell responses to bacterial interaction. Infect Disord Drug Targets 6:299-309