Antifungal Agent Target Identification: Synthetic Chemistry - Jacob Plattner

Abstract

Funding Agency

Agency: National Institute of Health (NIH)
Institute: National Institute of Dental & Craniofacial Research (NIDCR)
Type: Research Project (R01)
Project #: 1R01DE016835-01
Application #: 6951663
Study Section: Special Emphasis Panel (ZDE1-YL (13))

Project Start: 2005-07-01
Project End: 2007-07-01
Budget Start: 2005-07-01
Budget End: 2006-08-31
Support Year: 1
Fiscal Year: 2005
Total Cost: $624,282
Indirect Cost

Institution

Name: Anacor Pharmaceuticals, Inc.
Department
Type
DUNS #: 128824484

City: Palo Alto
State: CA
Country: United States
Zip Code: 94303

Related projects


NIH 2006 R01 DE	Target Identification of a Novel Antifungal Agent Plattner, Jacob A. / Anacor Pharmaceuticals, Inc.	$405,130
NIH 2005 R01 DE	Target Identification of a Novel Antifungal Agent Plattner, Jacob A. / Anacor Pharmaceuticals, Inc.	$624,282
NIH 2005 R01 DE	Antifungal Agent Target Identification: Synthetic Chemistry Plattner, Jacob A. / Anacor Pharmaceuticals, Inc.	$624,282

Publications

Seiradake, Elena; Mao, Weimin; Hernandez, Vincent et al. (2009) Crystal structures of the human and fungal cytosolic Leucyl-tRNA synthetase editing domains: A structural basis for the rational design of antifungal benzoxaboroles. J Mol Biol 390:196-207

Rock, Fernando L; Mao, Weimin; Yaremchuk, Anya et al. (2007) An antifungal agent inhibits an aminoacyl-tRNA synthetase by trapping tRNA in the editing site. Science 316:1759-61

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