Although dental implants are not yet the standard of care for edentulous patients, the use of this treatment option is rapidly increasing. The number of implants placed in the US increased by a factor of ten from 1983 to 2002 with $150 million of implant products sold to North American dentists in 2002. In the absence of implant placement, edentulism poses a serious health concern for US citizens. Without a tooth or implant to transfer loading to the alveolar bone, patients experience bone resorption with an average decrease of 4 mm in mandibular height within one year. It has been suggested that with proper treatment, achieving stable biointegration is no longer the primary factor limiting the lifetimes of implants. Fatigue fracture of the implant or the prostheses supported by the implant due to mechanical factors is a more prevalent cause of failure. Implant body diameter, prosthesis cementation method, and implant-abutment connection design have all been reported to significantly affect abutment screw loosening and fracture. It is clear that the dental implant community would benefit from systemic comparisons of implant designs, but such studies are not feasible without more efficient fatigue testing methods. The following specific aims are focused around our central goal of developing an efficient method for testing reliability of dental implants: 1) Correlate the results of finite element stress analysis to the fracture origin observed on physical specimens. 2) Verify the accuracy of step-stress method for estimating the mechanical reliability of dental implants over time. 3) Determine an acceleration factor to allow conversion between fatigue data collected at different cyclic frequencies. In lay terms, this project will enable future researchers to improve dental products by faster methods.

National Institute of Health (NIH)
National Institute of Dental & Craniofacial Research (NIDCR)
Research Project (R01)
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Study Section
Special Emphasis Panel (ZRG1-MOSS-K (02))
Program Officer
Drummond, James
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University of Mississippi Medical Center
Schools of Dentistry
United States
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Duan, Yuanyuan; Gonzalez, Jorge A; Kulkarni, Pratim A et al. (2018) Fatigue lifetime prediction of a reduced-diameter dental implant system: Numerical and experimental study. Dent Mater 34:1299-1309
Borba, Márcia; Duan, Yuanyuan; Griggs, Jason A et al. (2015) Effect of ceramic infrastructure on the failure behavior and stress distribution of fixed partial dentures. Dent Mater 31:413-22
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Borba, Márcia; Cesar, Paulo F; Griggs, Jason A et al. (2013) Step-stress analysis for predicting dental ceramic reliability. Dent Mater 29:913-8
Joshi, Gaurav V; Duan, Yuanyuan; Neidigh, John et al. (2013) Fatigue testing of electron beam-melted Ti-6Al-4V ELI alloy for dental implants. J Biomed Mater Res B Appl Biomater 101:124-30
Joshi, Gaurav V; Duan, Yuanyuan; Della Bona, Alvaro et al. (2013) Fatigue loading and R-curve behavior of a dental glass-ceramic with multiple flaw distributions. Dent Mater 29:1123-31
Borba, Marcia; de Araujo, Maico D; de Lima, Erick et al. (2011) Flexural strength and failure modes of layered ceramic structures. Dent Mater 27:1259-66
Borba, Marcia; Cesar, Paulo F; Griggs, Jason A et al. (2011) Adaptation of all-ceramic fixed partial dentures. Dent Mater 27:1119-26
Borba, Marcia; de Araujo, Maico D; Fukushima, Karen A et al. (2011) Effect of the microstructure on the lifetime of dental ceramics. Dent Mater 27:710-21

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