Abstract

The purpose of the proposed research is to examine the role of vitamin B-12 in the regulation of folic acid metabolism and the effect of thyroid status on folic acid and vitamin B-12. The specific objectives include: 1. The study of the metabolic relationship between folic acid, vitamin B-12 and methionine with special reference to their effects on folic acid polyglutamate formation. 2. The study of the effects of thyroxine status on the function of vitamin B-12 and folic acid. 3. The study of the biological effects of the folic acid antagonist """"""""x-methyl folic acid"""""""".

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK008171-23
Application #
3224556
Study Section
Nutrition Study Section (NTN)
Project Start
1978-01-01
Project End
1988-06-30
Budget Start
1986-09-01
Budget End
1988-06-30
Support Year
23
Fiscal Year
1986
Total Cost
Indirect Cost

  Institution

Name
University of California Berkeley
Department
Type
DUNS #
094878337
City
Berkeley
State
CA
Country
United States
Zip Code
94704