Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK015120-25
Application #
2136895
Study Section
Physical Biochemistry Study Section (PB)
Project Start
1976-04-01
Project End
1998-06-30
Budget Start
1995-07-01
Budget End
1998-06-30
Support Year
25
Fiscal Year
1995
Total Cost
Indirect Cost

  Institution

Name
University of Pennsylvania
Department
Biochemistry
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104

  Publications

Yang, L J; Guo, Y L; Trygankova, O et al. (1999) Epidermal growth factor and angiotensin II regulation of extracellular signal-regulated protein kinase in rat liver epithelial WB cells. Biochem Pharmacol 57:425-32
Guo, Y L; Kang, B; Williamson, J R (1999) Resistance to TNF-alpha cytotoxicity can be achieved through different signaling pathways in rat mesangial cells. Am J Physiol 276:C435-41
Guo, Y L; Kang, B; Yang, L J et al. (1999) Tumor necrosis factor-alpha and ceramide induce cell death through different mechanisms in rat mesangial cells. Am J Physiol 276:F390-7
Maloney, J A; Tsygankova, O M; Yang, L et al. (1999) Activation of ERK by Ca2+ store depletion in rat liver epithelial cells. Am J Physiol 276:C221-30
Pei, Z D; Williamson, J R (1998) Mutations at residues Tyr771 and Tyr783 of phospholipase C-gamma1 have different effects on cell actin-cytoskeleton organization and cell proliferation in CCL-39 cells. FEBS Lett 423:53-6
Tsygankova, O M; Peng, M; Maloney, J A et al. (1998) Angiotensin II induces diverse signal transduction pathways via both Gq and Gi proteins in liver epithelial cells. J Cell Biochem 69:63-71
Guo, Y L; Baysal, K; Kang, B et al. (1998) Correlation between sustained c-Jun N-terminal protein kinase activation and apoptosis induced by tumor necrosis factor-alpha in rat mesangial cells. J Biol Chem 273:4027-34
Guo, Y L; Kang, B; Williamson, J R (1998) Inhibition of the expression of mitogen-activated protein phosphatase-1 potentiates apoptosis induced by tumor necrosis factor-alpha in rat mesangial cells. J Biol Chem 273:10362-6
Maloney, J A; Tsygankova, O; Szot, A et al. (1998) Differential translocation of protein kinase C isozymes by phorbol esters, EGF, and ANG II in rat liver WB cells. Am J Physiol 274:C974-82
Guo, Y L; Peng, M; Kang, B et al. (1997) Inhibition of thrombin-stimulated cell proliferation by ceramide is not through inhibition of extracellular signal-regulated protein kinase. Biochem Biophys Res Commun 240:405-8

Showing the most recent 10 out of 35 publications