Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project (R01)
Project #
5R01DK017325-22
Application #
2137067
Study Section
Physiological Chemistry Study Section (PC)
Project Start
1976-06-01
Project End
1998-06-30
Budget Start
1995-07-01
Budget End
1998-06-30
Support Year
22
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Joslin Diabetes Center
Department
Type
DUNS #
071723084
City
Boston
State
MA
Country
United States
Zip Code
02215
Spiro, Robert G (2002) Protein glycosylation: nature, distribution, enzymatic formation, and disease implications of glycopeptide bonds. Glycobiology 12:43R-56R
Edge, A S; Spiro, R G (2000) A specific structural alteration in the heparan sulphate of human glomerular basement membrane in diabetes. Diabetologia 43:1056-9
Chandra, N C; Spiro, M J; Spiro, R G (1998) Identification of a glycoprotein from rat liver mitochondrial inner membrane and demonstration of its origin in the endoplasmic reticulum. J Biol Chem 273:19715-21
Karaivanova, V K; Spiro, R G (1998) Sulphation of N-linked oligosaccharides of vesicular stomatitis and influenza virus envelope glycoproteins: host cell specificity, subcellular localization and identification of substituted saccharides. Biochem J 329 ( Pt 3):511-8
Karaivanova, V K; Luan, P; Spiro, R G (1998) Processing of viral envelope glycoprotein by the endomannosidase pathway: evaluation of host cell specificity. Glycobiology 8:725-30
Spiro, R G; Bhoyroo, V D (1998) Characterization of a spleen sulphotransferase responsible for the 6-O-sulphation of the galactose residue in sialyl-N-acetyl-lactosamine sequences. Biochem J 331 ( Pt 1):265-71
Edge, A S; Spiro, R G (1997) Structure of the O-linked oligosaccharides from a major thyroid cell surface glycoprotein. Arch Biochem Biophys 343:73-80
Spiro, R G; Zhu, Q; Bhoyroo, V et al. (1996) Definition of the lectin-like properties of the molecular chaperone, calreticulin, and demonstration of its copurification with endomannosidase from rat liver Golgi. J Biol Chem 271:11588-94
Shen, G Q; Kresbach, G; Spiro, M J et al. (1995) Evaluation of the cell specificity and sulfate dependence of glomerular extracellular matrix proteoglycan synthesis. Arch Biochem Biophys 321:83-93
Spiro, M J; Spiro, R G (1992) Monosaccharide determination of glycoconjugates by reverse-phase high-performance liquid chromatography of their phenylthiocarbamyl derivatives. Anal Biochem 204:152-7

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